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HFE C282Y heterozygosity in hepatocellular carcinoma: evidence for an increased prevalence  Claus Hellerbrand, Andreas Pöppl, Arndt Hartmann, Jürgen Schölmerich,

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Presentation on theme: "HFE C282Y heterozygosity in hepatocellular carcinoma: evidence for an increased prevalence  Claus Hellerbrand, Andreas Pöppl, Arndt Hartmann, Jürgen Schölmerich,"— Presentation transcript:

1 HFE C282Y heterozygosity in hepatocellular carcinoma: evidence for an increased prevalence 
Claus Hellerbrand, Andreas Pöppl, Arndt Hartmann, Jürgen Schölmerich, Guntram Lock  Clinical Gastroenterology and Hepatology  Volume 1, Issue 4, Pages (July 2003) DOI: /S (03)

2 Figure 1 Serum ferritin levels in HCC patients with C282Y heterozygote (C282Y +/−) (n = 14) or C282Y wt (C282Y −/−) (n = 83) genotype. Bars represent median serum levels. Clinical Gastroenterology and Hepatology 2003 1, DOI: ( /S (03) )

3 Figure 2 Transferrin saturation (TFS) in HCC patients with C282Y heterozygote (C282Y +/−) or C282Y wt (C282Y −/−) genotype. Bars represent median TFS. Clinical Gastroenterology and Hepatology 2003 1, DOI: ( /S (03) )

4 Figure 3 Hepatic iron deposition comparing C282Y heterozygote (C282Y +/−) and wt (C282Y −/−) HCC patients. Iron deposition was analyzed in (A) HCC tissue (n = 113) and (B) nontumorous surrounding liver tissue (n = 83) using a semiquantitative histologic score. Clinical Gastroenterology and Hepatology 2003 1, DOI: ( /S (03) )


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