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A Journal Club on Lipid Management:

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Presentation on theme: "A Journal Club on Lipid Management:"— Presentation transcript:

1 A Journal Club on Lipid Management:

2 Program Goals

3 JUPITER Increased Incidence of T2D With Rosuvastatin

4 Statins and New-Onset T2D Meta-Analysis of 13 Clinical Trials

5 T2D Risk: No Difference Between Statins

6 T2D Risk Increases With Statin Potency Meta-Analysis of 5 Clinical Trials

7 Certain Statins Increase the Risk for New-Onset T2D

8 Pitavastatin Does Not Adversely Affect FBG, HbA1c, or T2D Development

9 Pitavastatin Has Neutral Effect on FBG Across the Dose Range

10 J-PREDICT Study Design

11 J-PREDICT Primary Outcome: Cumulative Incidence of Diabetes

12 TNT: Risk for New-Onset T2D Stratified by Risk Factors and Statin Dose

13 Risk for New-Onset T2D Stratified by Age

14 Multidisciplinary Team Approach to Reduce Risk for Diabetes

15 JUPITER: CV Benefit vs T2D Risk

16 Statin-Associated T2D Implications for Clinical Care

17 How Statins Could Impair Glucose and Insulin Metabolism

18 Statin Selection Consideration

19 Abbreviations

20 Abbreviations (cont)


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