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Hungry for Mechanism in Hippo Signaling

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Presentation on theme: "Hungry for Mechanism in Hippo Signaling"— Presentation transcript:

1 Hungry for Mechanism in Hippo Signaling
Cell  Volume 151, Issue 6, (December 2012) DOI: /j.cell Copyright © Terms and Conditions

2 Ras activation and mitochondrial dysfunction (green) stimulate cell proliferation (magenta) of surrounding cells (blue). Image courtesy of Tatsushi Igaki. Cell  , DOI: ( /j.cell ) Copyright © Terms and Conditions

3 Loss of LIFR causes lung metastasis of breast cancer cells, which can be reversed by depletion of YAP. Photos courtesy of Li Ma. Cell  , DOI: ( /j.cell ) Copyright © Terms and Conditions

4 Mo et al. suggest a role for a GPCR (rainbow) in regulating Hippo signaling.
Cell  , DOI: ( /j.cell ) Copyright © Terms and Conditions

5 Hipk expression (red) promotes Yki activity (white) in the Drosophila melanogaster wing imaginal disc. Images courtesy of Carole Poon and Kieran Harvey. Cell  , DOI: ( /j.cell ) Copyright © Terms and Conditions


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