1. Inactivation of Stat3 in tumor cells
Ana M Gamero, Howard A Young, Robert H Wiltrout 
Cancer Cell 
Volume 5, Issue 2, Pages (February 2004)
DOI: /S (04)

2. Figure 1
A model for the role of Stat3 in the regulation of tumor immunity
As shown in the left panel, activated Stat3 in cancer cells serves to constitutively inhibit T cell activation by inducing factors that impair DC maturation and activation, thus contributing to T cell tolerance. Conversely, as shown in the right panel, blocking Stat3 in tumor cells allows the production of factors that enable DC maturation and function, which contributes to T cell-mediated antitumor responses.
Cancer Cell 2004 5, DOI: ( /S (04) )