1. White adipose tissue (HFD)
High-fat diet (HFD)
Standard diet (SD)
AHR activation
Serum/plasma (HFD)
Whole body
Insulin ↔
Leptin ↔
Adiponectin ↔
FGF21 ↔
Glucose ↔
FFA ↔
Body weight gain ↔
Feed intake ↔
Glucose tolerance ↓
Insulin sensitivity ↔ (HFD)
Insulin sensitivity ↓ (SD)
Liver
SOCS3 ↓ (HFD)
Relative weight ↔
Triglyceride content ↑ (HFD)
Cholesterol content ↔
Lipogenesis ↑
Fatty acid uptake ↔ (HFD)
β-oxidation ↔ (HFD)
Gluconeogenesis ↔ (HFD)
Inflammation ↑ (HFD)
Oxidative stress ↑ (HFD)
Cholesterol biosynthesis ↑ (SD)
Skeletal muscle (HFD)
Triglyceride content ↔
White adipose tissue (HFD)
Relative weight ↔