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Managing IBD
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Treatment of IBD
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Management of IBD Sprint or Marathon?
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Challenges and Unmet Needs
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The Sprint
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When Sprinting Matters
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After the Sprint What Happens Next?
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The Marathon
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Long-Term Remission Why Is It Important?
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Colectomy Rates in Patients With UC Are Decreasing Swiss IBD Cohort Study
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Long-Term Remission Why Is It Important (cont)?
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Steroids for the Treatment of CD Benefit for the Patient
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Steroids for the Treatment of UC Symptomatic Control
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Thiopurines Prevent the Need for Surgery in CD
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Mucosal Healing as a Treatment Goal
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Step Up, Top Down Early Aggressive Therapy Causes Mucosal Healing in CD
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Achievement of Mucosal Healing With Immunomodulators and Biological Therapy
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Benefits of Biological Agents for CD
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Over Half of Patients Have a Primary or Secondary Loss of Response to Anti-TNF Therapies
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Lasting Clinical Remission With Vedolizumab 5-Year Cumulative Exposure Data
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Sustained Clinical Remission Rates With Ustekinumab (2-Year Data)
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Immunogenicity of Newer Therapies
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Best Practice for Managing the Sprint vs Marathon
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Treatment Options Choosing a Biological Therapy for the Marathon
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Evidence Beyond Clinical Trials on the Use of Vedolizumab and Ustekinumab
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VICTORY Consortium Vedolizumab vs Anti-TNF Therapy (Propensity Score-Matched Analysis)
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Key Considerations When Selecting a Therapy for an Individual Patient
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Treatment Persistency
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Targeting the Right Drug to the Individual Patient at the Right Time
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Monitoring Patients Beyond Clinical Symptoms
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Effective Infection Management May Improve Treatment Persistency
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Concluding Remarks
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Abbreviations
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