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Surgical quality of wedge resection affects overall survival in patients with early stage non–small cell lung cancer  Gaurav S. Ajmani, MHS, Chi-Hsiung.

Published byCatherine Beauchamp Modified over 6 years ago

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Presentation on theme: "Surgical quality of wedge resection affects overall survival in patients with early stage non–small cell lung cancer  Gaurav S. Ajmani, MHS, Chi-Hsiung."— Presentation transcript:

1 Surgical quality of wedge resection affects overall survival in patients with early stage non–small cell lung cancer  Gaurav S. Ajmani, MHS, Chi-Hsiung Wang, PhD, Ki Wan Kim, MD, John A. Howington, MD, Seth B. Krantz, MD  The Journal of Thoracic and Cardiovascular Surgery  Volume 156, Issue 1, Pages e2 (July 2018) DOI: /j.jtcvs Copyright © 2018 The American Association for Thoracic Surgery Terms and Conditions

2 Figure 1 Cohort selection from the National Cancer Database non–small cell lung cancer (NSCLC) participant user file. NSC, Non–small cell; CT, chemotherapy; RT, radiation therapy; SBRT, stereotactic body radiation therapy. The Journal of Thoracic and Cardiovascular Surgery  , e2DOI: ( /j.jtcvs ) Copyright © 2018 The American Association for Thoracic Surgery Terms and Conditions

3 Figure 2 Wedge resection quality and overall survival from diagnosis according to: (A) number of lymph nodes (LNs) examined, (B) margin status, and (C) overall surgical quality combining LNs examined and margin status. Results are presented as Kaplan–Meier curves with 95% confidence interval bands. R0, Negative margins; R1/R2, positive margins. The Journal of Thoracic and Cardiovascular Surgery  , e2DOI: ( /j.jtcvs ) Copyright © 2018 The American Association for Thoracic Surgery Terms and Conditions

4 Figure 3 SBRT compared with wedge resection and overall survival from diagnosis, among the propensity-matched cohort: (A) overall and (B) according to overall surgical quality combining nodes examined and margin status. Results are presented as Kaplan–Meier curves with 95% confidence interval bands. SBRT, Stereotactic body radiation therapy; R0, negative margins; R1/R2, positive margins; LN, lymph node. The Journal of Thoracic and Cardiovascular Surgery  , e2DOI: ( /j.jtcvs ) Copyright © 2018 The American Association for Thoracic Surgery Terms and Conditions

5 Figure E1 A, Standardized difference plot, and (B) mirror histogram showing subcohort balance after propensity score-matching. SCC, Squamous cell carcinoma; L, left; R, right; SES, socioeconomic status; AC, adenocarcinoma; BAC, bronchoalveolar carcinoma. The Journal of Thoracic and Cardiovascular Surgery  , e2DOI: ( /j.jtcvs ) Copyright © 2018 The American Association for Thoracic Surgery Terms and Conditions

6 Wedge resection quality and survival versus stereotactic radiation.
The Journal of Thoracic and Cardiovascular Surgery  , e2DOI: ( /j.jtcvs ) Copyright © 2018 The American Association for Thoracic Surgery Terms and Conditions

7 Video 1 Dr Krantz discussing the background and relevance of the study. Video available at: The Journal of Thoracic and Cardiovascular Surgery  , e2DOI: ( /j.jtcvs ) Copyright © 2018 The American Association for Thoracic Surgery Terms and Conditions

8 The Journal of Thoracic and Cardiovascular Surgery 2018 156, 380-391
The Journal of Thoracic and Cardiovascular Surgery  , e2DOI: ( /j.jtcvs ) Copyright © 2018 The American Association for Thoracic Surgery Terms and Conditions

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