1. Should I Stay or Should I Go?

3. Program Goals

4. Initiating Therapy

5. Predicting DMT Response

6. Therapeutic Selection

7. Prognostic Factors

8. NTZ: An Aggressive DMT

9. Rebound Effects When Switching DMTs

10. Defining Induction Therapies

11. Discussing DMTs With Patients

12. Natural Course of MS

13. Shared Decision Making

14. Brain Volume Loss

15. Adverse Events

16. Defining Inadequate Response

17. Breakthrough Disease Activity

18. Subclinical Disease Activity and NEDA

19. Deconditioning and Disability

20. Addressing Cognitive Changes

21. MRI Measures in MS

22. Switching Therapies in MS

23. NTZ and New MRI Lesions

24. Switching From NTZ

25. Switching Oral Therapies

26. Conclusions

27. Abbreviations