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B-cell Signaling: Protein Kinase Cδ Puts the Brakes on

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Presentation on theme: "B-cell Signaling: Protein Kinase Cδ Puts the Brakes on"— Presentation transcript:

1 B-cell Signaling: Protein Kinase Cδ Puts the Brakes on
Diane Mathis, George L King  Current Biology  Volume 12, Issue 16, Pages R554-R556 (August 2002) DOI: /S (02)

2 Figure 1 Different signals emanating from the B cell antigen receptor.
Left, events downstream of an activation stimulus (e.g. a foreign antigen). Right, events downstream of a tolerogenic stimulus (such as a soluble self-antigen). The upper curve represents the plasma membrane, and the inner represents the nuclear membrane. Ca2+ depicts the calcium signal, with the size of the triangle reflecting the strength and duration of this signal. ERK, extracellular signal regulated kinase; JNK, c-Jun N-terminal kinase; NFAT, nuclear factor of activated T cells; NFκB, nuclear factor κB. Current Biology  , R554-R556DOI: ( /S (02) )


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