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Chronic Diarrhea Due to Surreptitious Use of Bisacodyl: Case Reports and Methods for Detection
RICHARD D. KACERE, M.D. Mayo Clinic Proceedings Volume 68, Issue 4, Pages (April 1993) DOI: /S (12)60130-X Copyright © 1993 Mayo Foundation for Medical Education and Research Terms and Conditions
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Fig. 1 Mass spectrometry-gas chromatography, showing relative abundance of spectral components of bisacodyl and its metabolite in comparison with mass-to-charge ratio of fragments that result from electron bombardment. A, Unchanged bisacodyl in stool, showing characteristic electron ionization spectral pattern. B, Metabolite of bisacodyl, bisacodyl diphenol, was detected in urine of both patients who were taking bisacodyl surreptitiously and of seven patients who were given bisacodyl in preparation for colonoscopy. The metabolite has a characteristic spectral pattern that differs from that of the parent compound, bisacodyl. Mayo Clinic Proceedings , DOI: ( /S (12)60130-X) Copyright © 1993 Mayo Foundation for Medical Education and Research Terms and Conditions
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