1. Management of NGS data or tests in oncology
healthdata.be
Management of NGS data or tests in oncology
2nd Symposium “ Introduction of the Next-Generation-sequencing technology in routine clinical analysis in the Belgian healthcare “
Sponsored by
, Passage 44, Brussels

3. Roadmap “Next Generation Sequencing” started Q1 2016: Main focus of project = quality of NGS testing (KC) , secondary focus on epidemiology (BCR)
Precision Belgium project by the Belgian Society of Medical Oncology (BSMO) : in close collaboration with project team Roadmap “Next Generation Sequencing”: VCF-files will be used for inclusion patients in existing and new clinical trials of the BSMO.
Predictive Tests For A Therapeutic Response (PITTER): Main focus of project to collect epidemiological and outcome data on reimbursed tests and medicines, in order to assess and modify national recommendations and reimbursement policies.

4. Healthdata.be at a glance
Technical description of each data collection
healthdata.be
HD4DP
HD4RES
DATAWAREHOUSE
HEALTHSTAT
HD4DP = software “healthdata for data providers”
HD4RES = software “healthdata for researchers”
HD4PrC = software / API “healthdata for primary care”
HD4PrC = software “healthdata for patient reported outcomes”
API = “Application Programming Interface” (cfr. “Webservice”)         
Registration
in Primary System
Data Captation
Secure Data Transfer & encoding of IDs
Data Monitoring
Data Validation
Data Storage
Analysis
BI-Reporting
Annotation & Correction Request
Trusted Third Party for encryption and pseudonymization

6. 100% (of 117) 100% (of 9) 92% (of 87) 88% (of 150)
hospitals
Lab genetics
Lab Ana Path
Lab Clin Bio

7. DCD’s Final: n = 28
DCD’s draft: n= 12
Data Collection Definitions (DCD’s): list view

8. Data Collection Definitions (DCD’s): full description

9. DEMO environment: main portal

10. DEMO environment: NGS form example

11. Healthdata.be support center (documents, videos, FAQ, support request forms, contact details, …)

12. Roadmap NGS PRECISION Belgium PITTER HD4DP DCD TPR DWH HD SteerCo
Sect Comm
HD4DP
DCD
TPR
DWH
HD SteerCo
Sect Comm
Roadmap NGS
HD4DP
DCD
TPR
DWH
HD SteerCo
Sect Comm
PRECISION Belgium
PITTER

13. Think big, start small SAM/BAM-files FASTA-files VCF-files
Ongoing analysis of requirements and available technologies for transfer, management and analysis. First decisions and implementtions expected in 2018.
Start

14. Q&A www.healthdata.be healthdata@wiv-isp.be healthdata be
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