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in Early Adolescence and Escalations in Alcohol Use

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1 Phenotypic Differences as Moderators of the Association Between Social Context
in Early Adolescence and Escalations in Alcohol Use Matthew D. Scalco & Craig R. Colder Psychology Department, State University of New York at Buffalo U B University at Buffalo State University of New York U B University at Buffalo State University of New York BACKGROUND RESULTS Effortful Control x AUPP Trajectories of Alcohol Use (AU) and Alcohol Use Disorder (AUD) in Adolescence Structure of the Two Part Latent Growth Curve Model Probability of initiation of AU increases across adolescence There is variability in levels of use and trajectories of AU after initiation occurs (e.g., Colder et al., 2002) Only a portion of youth meet criteria for AUD (Anthony, Chen, & Storr, 2005; Sung et al., 2004) AUD symptoms are unusual prior to age 13 and increase to a peak between (Sung et al., 2004) Factors that can predict youth who will escalate in levels of AU and who are at increased risk for AUD after initiation are of interest to prevention and intervention efforts Both latent growth curves were parameterized such that the first indicator was set to 0 and the last indicator was set to 1. Remaining indicators were freely estimated to model the non-linear change that was apparent form descriptive statistics in each portion, which will now be referred to as the Binary (initiation of AU) and Continuous (levels of AU) portions, respectively. Nested chi-square tests suggested that all intercepts and growth factors had significant variability around the mean trends. Subsequently, mean centered IVs and interaction terms were added as predictors of each Intercept and Growth factor from each portion. B_Intercept B_Growth C_Intercept C_Growth AUPP 0.24 -0.15 0.28 0.01 CFAU 0.18 -0.16 0.08 0.06 EC -0.05 0.03 0.00 NA 0.12 -0.14 -0.21 SUR 0.07 0.02 SUR x CFAU -0.03 0.04 0.15 SUR x AUPP -0.10 NA x CFAU -0.04 0.05 0.10 NA x AUPP -0.07 0.09 EC x CFAU EC x AUPP 0.16 -0.20 AGE 0.19 0.27 0.21 INTERCEPTS 10.92 -1.47 2.83 R-Squared 0.20 0.32 Developmental Theory of AU and AUD Deviations in temperament are believed to interact with the environment, especially the social context in early adolescence to impact the liability for early initiation, escalation of AU, and AUD (Dawes et al., 2000; Vanyukov et al., 2012) Log Transformed Quantity by Frequency of Alcohol Use Temperament Surgency (SUR) High Intensity Pleasure, Shyness, and Affiliation (reward sensitivity, extraversion) Effortful Control (EC) Attention, Inhibitory Control, Activational Control (executive functioning) Negative Affect (NA) Fear, Frustration/Irritability (emotional distress) SUR and EC have been linked to the initiation and escalation of AU Note. Bolded values = p < 0.05 and italicized and bolded values are p > 0.05 and p < B = Binary or Initiation of AU and C = Continuous or Levels of AU. CFAU = close friend alcohol use; AUPP = alcohol use with parents permission; SUR = Surgency; EC = Effortful Control; and Negative Affect = NA. Social Factors Surgency x CFAU Close friend AU (CFAU) and AU with parents permission (AUPP) Each linked to initiation and CFAU to escalation of SU (Cruz et al., 2012; Scalco et al., 2015; Zehe et al., 2015) Hypothesized to operate via socialization mechanisms Different temperaments may increase or decrease risk for this process Synthesis Summary of Results Superimposing developmental theories of AU and AUD on the empirical literature suggests: Temperament x CFAU/temperament x AUPP may predict who will have escalations in AU Testing this question requires separating initiation of AU from growth in levels of AU Two part growth model (Olsen & Schafer, 2001) As hypothesized the social factors had main effects on initiation at baseline and growth in the probability of initiating, but interacted with temperament to predict levels of AU The one exception is EC x AUPP which predicted all growth outcomes The combination of (1) CFAU with high SUR and (2) AUPP with either high SUR or low EC led to higher levels of AU at baseline and throughout adolescence Low SUR in conjunction with CFAU and high SUR without CFAU = increases in AU But did not surpass the sample level trend until later in adolescence (16 – 17) Log Transformed Quantity by Frequency of Alcohol Use Study Hypotheses H1: Surgency, Effortful Control, Negative Affect, Close Friend AU, and AU with parents permission will all predict early initiation of AU without parents permission High Surgency, Low Effortful Control, Low Negative Affect, High CFAU, and AUPP will all predict higher probability of AU initiation H2: Interactions, Surgency x CFAU, Surgency x AUPP, Effortful Control x CFAU, Effortful Control x AUPP, Negative Affect x CFAU, and Negative Affect x AUPP will predict escalations in AU, specifically Combinations of the predictions above (e.g., High Surgency and High CFAU) will lead to increases in levels of AU across adolescence (age: 11-18) CONCLUSIONS Developmental Theories and Trajectories of Alcohol Use (AU) in Adolescence There were largely main effects for initiation of AU Social environment impacts early initiation of AU regardless of temperament Poor regulation + parental permission for AU further increased risk for initiation However, levels of AU were predicted by several interactions High SUR + CFAU and AUPP = highest risk Low EC + AUPP = second highest risk Supports developmental theories which suggest that the social environment and temperament interact to deflect trajectories toward and away from risk for AUD Surgency x AUPP METHOD Social Exclusion Condition Control Condition Participants were drawn from two six wave longitudinal studies designed to test risk and protective factors for adolescent SU. Inclusion criteria were a 10 to 12 year-old child at the time of recruitment with no language or physical disabilities that would preclude participation. The 2 community samples included 387 and 378 families for a total of 765 families. The mean age for adolescents at the first assessment was 11.8 (SD = .79). Subsequent assessments occurred annually. At W1-W3 for both samples, target adolescents provided the names of four close friends and one was recruited into the study (close friend peer) to provide collateral reports. Peers were required to be within two years of age of the target adolescent and could not be a sibling. Attrition rate by W3 was 6.5% and completers vs. non-completers did not differ on any demographic or study variables. Measures Implications and Future Directions Log Transformed Quantity by Frequency of Alcohol Use Adolescent and Peer SU. Items taken from The National Youth Survey (NYS) were used to assess self-reported peer and adolescent lifetime and past year quantity and frequency of alcohol use “without parents permission” at each wave of assessment (Elliott & Huizinga, 1983). Lifetime use of alcohol with parental permission was assessed with a dichotomous item at W1. Temperament. The Early Adolescent Temperament Questionnaire-Revised (EATQ-R, Ellis & Rothbart, 2001), a parent report measure, was used to assess target adolescent temperament at W1. The EATQ-R includes 8 subscales, which combine to form three broad dimensions, including surgency, negative affect, and effortful control (Cronbach’s alpha were .83, .73, and .89 respectively). Evidence for the validity of this structure has been provided with high test retest correlations at the latent level (0.81 – 0.94; M = 0.88; Scalco, Lengua, & Colder, 2015). AU with parent permission in the context of poor regulation or high reward sensitivity and extraversion led to increases in levels of AU without permission Although more research is needed, this may suggest that “supervised drinking” in the context of certain traits in early adolescence (Mage = ) promotes problematic drinking Close friend AU in the context of high reward sensitivity and extraversion also led to higher initial levels of AU (Mage = 12.8) and steady increases throughout adolescence Future work may replicate, look at contextual variables (e.g., parties, dinner, etc.) related to early AU with parents permission, continuous measures of AU with parents permission, and whether temperament/social contexts transacts with AU Control Condition Data Analytic Plan A Two-Part Latent Growth Curve Model was run on qxf indices across 6 waves of longitudinal data (W1-W6). Binary portion = W1-W6 and Continuous portion = W2-W6 (allows for temporal precedence; moreover, levels of AU were very low at W1) The Santora Bentler Chi-square test was used to test whether adding variances and covariances improved model fit. Qxf indices were log transformed to meet distributional assumptions as is common in these models (Olsen & Schafer, 2001; Muthen, 2001). Age served as a control variable for all models. Surgency, Effortful Control, Negative Affect, CFAU and AUPP were then added as predictors of the growth factors. All IV’s were mean centered. Finally all 2-way interactions were added. For significant interactions: Model implied trajectories were plotted at combinations of the moderator (-1 SD, +1 SD) and IVs (USE/NO USE). This research was supported by two grants from NIDA (R01 DA and R01 DA019631) awarded to Dr. Craig Colder. The content of this poster is solely the responsibility of the authors and does not necessarily represent the official views of NIDA. Correspondence should be addressed to Matthew Scalco, B.A., Psychology Department, Park Hall, University at Buffalo, State University of New York, Buffalo, NY


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