1. OIE Regional Activities related measures against FMD
Oudom Xay,Laos
22-24 January 2007
OIE Regional Representation
for Asia and the Pacific, Tokyo
Y. Oketani

2. Ｃｏｎｔｅｎｔｓ FMD situation OIE Guidelines GF-TADs OIE Information Workshop
OIE Epidemiology Workshop
OIE Veterinary Drug Workshop

3. OIE World Organisation for Animal Health
an intergovernmental organisation
founded in 1924
by 28 countries
predates the UN
167 Member Countries
headquarters in Paris
5 Regional Representatives (Tokyo, Japan for Asia and the Pacific)

4. OIE’s international standards

5. Regional Steering Committees
GF-TADｓ
OIE HQ
Steering Committee
OIE/FAO/Donors
FAO
(AGA)
Global
Management Committee
Joint FAO/OIE Secretariat
Five Regional Commissions
Regional
OIE Regional Representations/FAO Regional Structure
Regional Steering Committees
OIE, FAO, Regional Specialised Organizations (RSOs), Specific donors
　Sub-regional
RSU
RSU
RSU
National
Veterinary Service, Diagnostic Laboratory, Others

6. GF-TADs Southeast Asia FMD
Regional Steering Committee
Secretariat: OIE Tokyo
Regional Specified Organization
ASEAN
Regional Supporting Unit
Epidemiology Unit
National
Institute
Reading
Institute
National
Institute l
National
Institute
National
Institute
National
Institute

7. Questionnaire for BSE Status Recognition
                                                                                                                                                                                                                                                                                    
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8. Animal Movemet Management

9. GF-TADs Southeast Asia HPAI
Regional Steering Committee
Secretariat: OIE Tokyo
Regional Specified Organization
ASEAN
Regional Supporting Unit
ASEAN Secretariat
Epidemiology
Unit
Reading
Institute
Reading
Institute
National
Institute l
National
Institute
National
Institute
National
Institute

10. Main constraints to Disease control
national veterinary services
Often no appropriate legislation in place
Weakness of disease reporting sistem
Limited ability to control animal movements and to increase biosecurity
Difficulty of implementing stamping out and vaccination
Insufficient laboratory diagnostic capacity and capability

11. Important lessons learned
Early detection and rapid adequate response has prevented spread and persistence of disease in some countries
Delayed detection and response, and too much decentralization has led to persistence of the virus in other countries
Some developing and in transition countries are at the limit of their abilities to eradicate the disease
Improvement of governance, including strong national chain of command is essential!!

12. OIE Project Coordinator
ＯＩＥ/Japan Special Trust Fund Project for HPAI Control in Southeast Asia
Government of Japan
OIE Paris
FAO
Coordination Committee & Steering Committee
OIE Tokyo
FAO Bangkok
OIE Project Coordinator
Regional Level
Development of Regional Control Strategies
Capacity building:
Software; ①Support to Control Strategy Development, ②Capacity building of diagnosis and surveillance, etc., ③Training for Field veterinarians and para-professionals on strategic surveillance (meetings, hands-on workshops, etc.), ④Information sharing
Hardware; Provision of laboratory diagnostic equipment and materials for capacity building
Development of Information System
National Level
Development of National Strategies and Training

13. Activities of the Special Trust Fund Project
Japan/OIE Special Trust Fund Project in S.E. Asia (1)
To encourage the improvement of regional and national HPAI control strategies including the development of contingency plans
2. To encourage HPAI information sharing to further strengthen regional early warning systems
3. To strengthen diagnostic capacity of regional collaborating laboratories and national reference/diagnostic laboratories for HPAI including the holding of training courses on advanced HPAI diagnosis and installment of high performance diagnostic equipment and materials
4. To train field veterinarians and para-professionals on HPAI strategic surveillance

14. 　RT-PＣＲ ＆ ＤＮＡ Sｅｑｕｅｎsｅｒ　　

15. Major Equipment List for the Laboratories
Centrifuge,
Incubator,
Supplementary Equipment,
Reagents,
Etc.
Cycler for Real-Time PCR
Sequencer
(for central ref. lab)
Biosafety Cabinet C II
Review of Lab Equipment of Respective Laboratories
Identification of the Equipment and Materials
Distribution/Installment of the Equipment for the Laboratories 10

16. Selection: Laboratory List for Strengthening Diagnostic Capacity
Under the OIE Project
<Countries> < Laboratories> < Location >
Cambodia National Animal Health and Production Phnom Penh
Investigation Center
Indonesia Disease Investigation Center, Region I (Medan) Medan City, North Sumatra Province
2. Disease Investigation Center, Region IV (Wates) Wates District, Yogyakarta Province
3. Veterinary Research Institute (Bogor) Bogor City, West Java Province
Laos National Animal Health Center Vientiane
Malaysia Veterinary Research Institute (Ipoh) Ipoh City
Myanmar Central Diagnostic Veterinary Laboratory Yangon
2. Mandalay Regional Laboratory Mandalay
Philippines Animal Health Center Quezon City
2. Regional Field Unit II Cagayan, Northern Luzon
3. Regional Field Unit VII Cebu Island
4. Regional Field Unit X Cagayan, Mindanao
Thailand Northeastern Veterinary Research And Development Center, Lower Zone Surin Province
2. Northeastern Veterinary Research And Development Center, Upper Zone Khon Kaen Pro.
3. National Institute of Animal Health Bangkok
Vietnam National Center for Veterinary Diagnosis Hanoi
2. Ho Chi Minh City Regional Diagnostic Center Ho Chi Minh
3. Can Tho Regional Diagnostic Center Can Tho
4. National Institute of Veterinary Research Hanoi 8

17. Location of the Laboratories
Mandalay
Hanoi
(2)
Yangon
Vientiane
Cagayan
Khon Kaen
Surin
Quezon
BKK
Phnom Penh
Cebu
Ho Chi Minh
Can Tho
Cagayan
Ipoh
Medan
Bogor
Wates (Yogyakarta)

24. Real Time PCR Diagnosis in the Field
Sample preparation (Homogenized etc.)
Step one: Class III Glovebox
Sampling in the field
(AI infection suspected)
Mini-CFG
Extract RNA
Step II: Class III/ II Glovebox
Real Time PCR Process
Tentative
Diagnosis in
the Field
RT-PCR Preparation
：PCR Hood
Micro-CFG

25. OIE Regional Information Workshop
WAHIS Information Workshop was held in Bangkok
Procurment computer systems
to report
Diseases
Obligations of Member Countries
based on
Infections
Other epidemiological events

26. OUTBREAKS OF H5N1 IN ANIMALS
~December 2005
~December 2005
(only wild birds)
Continuing from 2003
Continuing from 2003
(only wild birds)
2006 January~
2006 January~
(only wild birds)

27. OUTBREAKS
~December 2005
(Subtype H5)

28. OIE/CIRAD Regional Workshop on Epidemiology
OIE/CIRAD organized Regional Epidemiology Workshop in Bangkok in 2006
OIE will hold the National Epidemiology Workshop in collaboration with CIRAD in Manikla, Philippines 29 January-2 February and in Jakalta, Indonesia, February 2007.

29. OIE/VICHRegional Workshop on Harmonization of Veterinary Drugs
To harmonize Veterinary Grugs administration procedure and inspection technics, OIE held a Regional Workshop on Harmonization of Veterinary Drugs in Bogor, Indonesia, in October 2006.

30. Vaccination Guidelines: Country situation
Epidemiological situation
Poultry production systems
Logistical factors (vet services, cold chain)
Diagnostic capacity
Compensation mechanism
Objective of the campaign (emergency, preventive, routine)
Strategy (mass, targeted, ring)
Monitoring
Financial Resources

31. Development of Guidelines on the implementation of AI Vaccination
To establish detailed guidelines and a decision tree for the application, monitoring, precautionary measures of vaccination strategies
Guidelines distributed during the Vienna Conference To guide countries in their decisions whether to implement vaccination programs or not
World Conference on AI Vaccination
in March 2007

32. Agreement for virtual vaccine bank for Africa between OIE, AU/IBAR and Donors
AU/IBAR/PACE assess needs of countries and order the vaccines through OIE
OIE manages a vaccine bank and selects the companies complying with OIE standards on quality of vaccines through an international call for tenders
This concept could be extended worldwide

33. Thank you for your attention !!!
OIE Tokyo