1. Volume 121, Issue 6, Pages 1275-1280 (December 2001)
WNT1 inducible signaling pathway protein 3, WISP-3, a novel target gene in colorectal carcinomas with microsatellite instability 
Lin Thorstensen, Chieu B. Diep, Gunn I. Meling, Trude H. Aagesen, Christian H. Ahrens, Torleiv O. Rognum, Ragnhild A. Lothe 
Gastroenterology 
Volume 121, Issue 6, Pages (December 2001)
DOI: /gast
Copyright © 2001 American Gastroenterological Association Terms and Conditions

2. Fig. 1
Frequency of frameshift mutations in 11 genes in primary colorectal carcinomas with MSI. (Blue bar), results of the present study; and (white bar), mean mutation frequency evaluated from previous reports. *Target genes investigated by several groups and the mutation frequency range were: TGFβRII, 63%–93%26,35-39; BAX, 31%–67%10,11,35,36,38-40; hMSH3, 29%–64%11,35,36,38,39,41; and hMSH6, 12%–50%.11,35,36,38,39,41
Gastroenterology  , DOI: ( /gast )
Copyright © 2001 American Gastroenterological Association Terms and Conditions

3. Fig. 2
Frameshift mutations in a novel downstream target gene, WISP-3, in colorectal carcinomas with MSI. To the left, the PCR fragment analyses on an ABI PRISM 310 Analyzer are shown (the numbers in the blue boxes indicate the size of the PCR products). Sequenced PCR products of the normal sample and 1 tumor (C1314) are shown to the right. Tumors C1141 and C1314 reveal mutations in WISP-3. wt, wild-type; mut, mutation.
Gastroenterology  , DOI: ( /gast )
Copyright © 2001 American Gastroenterological Association Terms and Conditions