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Thiazide-Associated Hyponatremia, Report of the Hyponatremia Registry: An Observational Multicenter International Study Burst et al. Am J Nephrol 2017;45:420-430.

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Presentation on theme: "Thiazide-Associated Hyponatremia, Report of the Hyponatremia Registry: An Observational Multicenter International Study Burst et al. Am J Nephrol 2017;45:420-430."— Presentation transcript:

1 Thiazide-Associated Hyponatremia, Report of the Hyponatremia Registry: An Observational Multicenter International Study Burst et al. Am J Nephrol 2017;45: (DOI: / ) Table 1. Baseline demographics and clinical characteristics

2 Thiazide-Associated Hyponatremia, Report of the Hyponatremia Registry: An Observational Multicenter International Study Burst et al. Am J Nephrol 2017;45: (DOI: / ) Table 2. Baseline biochemical parameters

3 Thiazide-Associated Hyponatremia, Report of the Hyponatremia Registry: An Observational Multicenter International Study Burst et al. Am J Nephrol 2017;45: (DOI: / ) Fig. 1. Differential diagnosis of SAIDH vs. TIH. ORs and 95% CIs for clinical and biochemical parameters calculated by univariate logistic regression.

4 Thiazide-Associated Hyponatremia, Report of the Hyponatremia Registry: An Observational Multicenter International Study Burst et al. Am J Nephrol 2017;45: (DOI: / ) Table 3. Effectiveness and overcorrection of HN therapy options in TAH and SIADH patients

5 Thiazide-Associated Hyponatremia, Report of the Hyponatremia Registry: An Observational Multicenter International Study Burst et al. Am J Nephrol 2017;45: (DOI: / ) Fig. 2. Success rate for Δ24h[Na+] 5 mEq/L but ≤12 mEq/L for distinct therapies in TAH. HS, hypertonic saline; NS, isotonic saline; FR, fluid restriction; withdrawal, immediate withdrawal of thiazide, no withdrawal; delayed or no withdrawal of thiazide. Data for tolvaptan not included in statistical testing due to low number. HS/withdrawal vs. NS/no withdrawal: p = HS/withdrawal vs. FR/withdrawal: p = HS/withdrawal vs. no therapy/withdrawal: p = HS/withdrawal vs. FR/no withdrawal: p = HS/withdrawal vs. no therapy/no withdrawal: p <  n = number of patients


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