1. Nuno Bandeira Digitizing MS-enabled biology
Reference
lookup
“De novo”
interpretation
How good/important is this identification?
Which spectra were identified before and why do they matter?
What are the similar datasets?
What are the most important or common unidentified spectra?
Who analyzes similar data?

2. Core Expertise: Large scale algorithms and computational analysis
Big Data
Big Algorithms
Thousands of datasets,
tens of billions of spectra
Designed to build on rather than
just ‘tolerate’ big data
Big Compute
Big Community
Proteomics Scalable, Accessible
and Flexible environment
Dozens of advanced workflows
scalable to thousands of cores
Empower and enable community-wide
sharing of knowledge

3. Proposed Collaborations with SSPPS Faculty
Identify everything, every time ?
Mono/Polyclonal antibodies, unsequenced organisms
Interactions, conjugates
MHC-I/II, endogenous peps
Natural products
Quantify knowns and unknowns
Remember everything that matters and why
Therapeutic implications
Structural
and
functional context
Deep characterization
Comprehensive characterization