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Patients With T2D Presenting With Glycosuria: Examining the SGLT2 MOA

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Presentation on theme: "Patients With T2D Presenting With Glycosuria: Examining the SGLT2 MOA"— Presentation transcript:

1 Patients With T2D Presenting With Glycosuria: Examining the SGLT2 MOA

2

3 Goals

4 Diagnosed Diabetes,

5 Despite Increasing Prevalence, T2D Remains Undertreated

6 Limitations of Conventional Glucose-Lowering Agents

7 Limitations of Conventional Glucose-Lowering Agents (cont)

8 The Need for Novel Antihyperglycemic Agents

9 Pathophysiologic Pathways Affecting Glycemic Control in T2D

10 SGLT2 and Glucose Control

11 SGLT2: Novel Target for Glucose Control

12 Currently FDA-approved SGLT2 Inhibitors

13 Glycosuria: Concerns in Urgent Care Settings

14 Clinical Trial Findings for SGLT2 Inhibitors

15 Clinical Trial Findings for SGLT2 Inhibitors: Extraglycemic Effects

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18 SGLT2 Inhibitors: Risk of Hypotension

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20 Treating Patients With Type 2 Diabetes and CKD

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22

23 Abbreviations

24 Abbreviations (cont)

25 References

26 References (cont)

27 References (cont)

28 References (cont)

29 References (cont)

30 References (cont)

31 References (cont)


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