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Omega 3 – Omega 6: What is right for the liver?

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Presentation on theme: "Omega 3 – Omega 6: What is right for the liver?"— Presentation transcript:

1 Omega 3 – Omega 6: What is right for the liver?
Ashraf Mohammad El-Badry, Rolf Graf, Pierre-Alain Clavien  Journal of Hepatology  Volume 47, Issue 5, Pages (November 2007) DOI: /j.jhep Copyright © 2007 European Association for the Study of the Liver Terms and Conditions

2 Fig. 1 Eicosanoid synthesis from dihomo-γ-linoleic acid (DGLA), arachidonic acid and eicosapentaenoic acid (EPA). LT, leukotriene; PG, prostaglandin; TX, thromboxane (modified from: Simopoulos AP. World Rev Nutr Diet 2003;92:1–22). Journal of Hepatology  , DOI: ( /j.jhep ) Copyright © 2007 European Association for the Study of the Liver Terms and Conditions

3 Fig. 2 PUFA-mediated lipid accumulation in the liver which possibly influences the histological pattern of hepatic steatosis. ACO, acyl-CoA oxidase; apo B-100, apolipoprotein B-100; CPT-1, carnitine palmitoyl transferase-1; FAS, fatty acid synthase; NF-Y, nuclear factor-Y; PPAR-α, peroxisome proliferator activated receptor-α; SCD-1, stearoyl Co-A desaturase-1; SREBP-1, sterol regulatory element binding protein-1. Journal of Hepatology  , DOI: ( /j.jhep ) Copyright © 2007 European Association for the Study of the Liver Terms and Conditions


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