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Volume 52, Issue 3, Pages (September 2007)

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Presentation on theme: "Volume 52, Issue 3, Pages (September 2007)"— Presentation transcript:

1 Volume 52, Issue 3, Pages 760-768 (September 2007)
FGFR3 Mutations and a Normal CK20 Staining Pattern Define Low-Grade Noninvasive Urothelial Bladder Tumours  Johanna M.M. van Oers, Peter J. Wild, Maximilian Burger, Stefan Denzinger, Robert Stoehr, Elke Rosskopf, Ferdinand Hofstaedter, Ewout W. Steyerberg, Monika Klinkhammer-Schalke, Ellen C. Zwarthoff, Theodorus H. van der Kwast, Arndt Hartmann  European Urology  Volume 52, Issue 3, Pages (September 2007) DOI: /j.eururo Copyright © 2007 European Association of Urology Terms and Conditions

2 Fig. 1 Immunohistochemical staining with CK20. (A) Normal CK20 expression pattern in which only the superficial urothelial cells are positive. (B) Abnormal CK20 staining pattern, represented by CK20 expression in all cell layers. European Urology  , DOI: ( /j.eururo ) Copyright © 2007 European Association of Urology Terms and Conditions

3 Fig. 2 Kaplan-Meier analyses for disease-specific survival – (A) FGFR3, (B) Ki-67, (C) TP53, and (D) CK20. European Urology  , DOI: ( /j.eururo ) Copyright © 2007 European Association of Urology Terms and Conditions

4 Fig. 3 Combination of FGFR3 status and CK20 IHC compared to stage (A) and grade (B). mut=mutant FGFR3; wt=wild-type FGFR3; normal=normal CK20 staining pattern; abnormal=abnormal CK20 staining pattern. European Urology  , DOI: ( /j.eururo ) Copyright © 2007 European Association of Urology Terms and Conditions


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