1. Dabigatran vs Warfarin in Patients with Atrial Fibrillation – Results
Outcome
Event rate
RRR
ARR
Time
(yrs)
NNT
95% CI
Warfarin
Dabi 150 mg
Stroke embolism
3.3%
2.2%
33.3%
1.1% 2 91
59 – 194
Connolly SJ NEJM 2009
For this outcome the intervention shows benefit. (ARR = absolute risk reduction, RRI = relative risk reduction, NNT = number needed to treat)

2. Dabigatran vs Warfarin in Patients with Atrial Fibrillation – Results
Outcome
Event rate
RRI
ARI
Time
(yrs)
NNH
95% CI
Warfarin
Dabi 150 mg
Serious AEs
1.7%
2.7%
56.7% 1% 2
101
66 – 217
Connolly SJ NEJM 2009
For this outcome the intervention shows harm. (ARI = absolute risk increase, RRI = relative risk increase, NNH = number needed to harm)