1. Integrated Multiplex Assay and Sampling System (IMASS™ ) Training Presentation

2. BBI Detection - IMASS Training
22/04/2013
BBI Detection IMASS Training Presentation
IMASS DEVICES – INNOVATION IN HAND HELD
BIOLOGICAL AND EXPLOSIVE SAMPLING AND DETECTION

3. The IMASS (Integrated Multiplex Assay and Sampling System) device is a fast, robust and easy-to-use solution for rapid identification, particularly in high pressure situations:
Sample directly onto the device
8 assay sticks run simultaneously from a single sample
Ergonomic patented design is easy to use even in PPE
Device key points:
Coloured lid for identification
Up to 8 assay strips (with identifiers)
Driving nut with nub
Sponge frits
Sampling sponge connected to assay strips

4. Each box* of IMASS Device contains:
10 devices per box
10 buffer bottles
10 aide memoires
1 instruction leaflet
Weight and dimensions:
Each device is 3oz, 5.5” x 1.6” x 1.6”. (85g, 14cm x 4cm x 4cm).
Each box of 10 devices
is 2.7 lbs, 10.2” x 8.3” x 7.1” (1.22kg, 26cm x 21cm x18cm).
BBI
*Custom packs may be available

5. BBI Detection - IMASS Training
22/04/2013
BBI Detection IMASS Training Presentation
IMASS DEVICES – DEVELOPMENT SUMMARY

6. IMASS Devices were developed to solve problems with current detection systems such as;
Multiple components - Swab, Buffer, Test Strip
Difficult to handle when fully encumbered
Increased risk of error
Multiple assays to run
Poor sampling
Need to ensure all components available
To fill a need for rapid identification of multiple potential materials from a single sample.

7. The Solution:
An integrated sampling device that can be used to swab a surface and collect a sample, allowing immediate identification.
A device that can incorporate up to 8 separate lateral flow diagnostic strips.
Robust and can be used when wearing gloves.
Self-contained, no added reagents or power source.
Sample is retained for further testing or audit.
No power requirement.

8. Dstl developed and patented the IMASS Concept -TRL 3.
IMASS IP and antibodies were then licensed to BBI Detection through Ploughshare to allow commercial development.
BBI Detection working in partnership with Dstl technical team refined designs and generated moulded prototypes.
Prototypes evaluated by Dstl through agent and toxin testing and final modifications made to mould/strip design prior to scale up to routine manufacture.
Biothreat IMASS Commercially launched in 2013 and Explosive Detection system development was initiated.
Explosive Detection IMASS launched October 2015.

9. BBI Detection - IMASS Training
22/04/2013
BBI Detection IMASS Training Presentation
IMASS DEVICES – HOW IT WORKS

10. Biothreat Detection IMASS Device contains tests to detect the following 8 biothreat agents:

11. Explosive Detection IMASS Device contains tests to detect the following 6 explosive or explosive pre-cusrors:

12. IMASS – How it works step by step (powder)
Remove cap from buffer container
Unscrew cap from IMASS device
Add entire volume of buffer to IMASS sponge
Sample powder (match head size amount) or surface
Replace coloured cap and fully tighten
Fully engage grey driving nut, then place device vertically on flat surface, cap down.
Read tests after 15 minutes for Biothreat IMASS and 3 minutes for Explosive IMASS
Sponge Compression

13. Biothreat Detection IMASS interpretation
Biothreat Detection IMASS interpretation Explosive Detection IMASS interpretation

14. BBI Detection - IMASS Training
22/04/2013
BBI Detection IMASS Training Presentation
IMASS DEVICES – KEY FEATURES AND BENEFITS

15. IMASS Device Key Features
Up to 8 assay strips run simultaneously from 1 sample
Can sample surfaces, solids and liquids
Results in 3 to 15 minutes
Highly specific and highly sensitive tests
Easy to use in high pressure situations
Easy to understand results
Low amount of training required – can be used by non-specialists
No power requirement

16. IMASS Device Key Benefits
Increased sampling area
Ideal format for end users forced to make on the spot decisions
Rugged
No sample preparation required
Easily portable
Sponge/frit design ensures filtration of large particles from sample
Can be decontaminated after sampling
Sample retained for confirmatory lab analysis

17. IMASS Training and Training Devices
Specially designed training IMASS™ devices can be supplied for user training/assessments.
These devices enable the instructor to demonstrate the correct use of the device in a training environment, and also to assess the user’s ability to utilise the device.

18. BBI Detection - IMASS Training
22/04/2013
BBI Detection IMASS Training Presentation
IMASS DEVICES – MARKETS AND APPLICATIONS

19. IMASS – Markets a