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Infection of vascular prostheses caused by bacterial biofilms

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Presentation on theme: "Infection of vascular prostheses caused by bacterial biofilms"— Presentation transcript:

1 Infection of vascular prostheses caused by bacterial biofilms
Thomas M. Bergamini, M.D., Dennis F. Bandyk, M.D., Dean Govostis, M.D., Hermann W. Kaebnick, M.D., Jonathan B. Towne, M.D.  Journal of Vascular Surgery  Volume 7, Issue 1, Pages (January 1988) DOI: / (88) Copyright © 1988 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

2 Fig. 1 Scanning electron micrograph of knitted Dacron graft colonized in vitro with slime-producing S. epidermidis shows numerous adherent bacterial microcolonies enclosed within a surface biofilm. Area delineated by inset (A) is shown at higher magnification in (B) (bar indicates 10 μm). Journal of Vascular Surgery 1988 7, 21-30DOI: ( / (88) ) Copyright © 1988 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

3 Fig. 2 Canine aortic vascular prosthetic infection from a bacteria-laden biofilm. Findings of an S. epidermidis biofilm infection included perigraft inflammation, perigraft cavity with fluid, and the absence of graft incorporation. Journal of Vascular Surgery 1988 7, 21-30DOI: ( / (88) ) Copyright © 1988 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

4 Fig. 3 Histologic cross sections of canine aorta immediately adjacent to infected vascular prosthetic graft stained with hematoxylin-eosin. A, Wall thickening caused by edema and acute inflammation of the media and adventitia (original magnification ×63). Arrow indicates suture tract. B, Higher magnification of A shows giant cells (open arrow) next to suture tract and multiple foci of polymorphonuclear leukocytes (original magnification ×160). Journal of Vascular Surgery 1988 7, 21-30DOI: ( / (88) ) Copyright © 1988 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions


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