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Reassessing the Current UICC/AJCC TNM Staging for Renal Cell Carcinoma

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Presentation on theme: "Reassessing the Current UICC/AJCC TNM Staging for Renal Cell Carcinoma"— Presentation transcript:

1 Reassessing the Current UICC/AJCC TNM Staging for Renal Cell Carcinoma
Holger Moch, Walter Artibani, Brett Delahunt, Vincenzo Ficarra, Ruth Knuechel, Francesco Montorsi, Jean-Jacques Patard, Christian G. Stief, Tullio Sulser, Peter J. Wild  European Urology  Volume 56, Issue 4, Pages (October 2009) DOI: /j.eururo Copyright © 2009 European Association of Urology Terms and Conditions

2 Fig. 1 Macrophotograph of a clear cell renal cell carcinoma of the upper pole invading the perinephric fat (arrow) but not beyond the Gerota fascia. European Urology  , DOI: ( /j.eururo ) Copyright © 2009 European Association of Urology Terms and Conditions

3 Fig. 2 (A) Diagram showing the renal sinus fat (S) and its rich venous system that envelopes the collecting system. The renal capsule terminates (arrow) just inside the vestibule of the hilus. (B) A renal cell carcinoma (RCC) is constrained by the renal capsule (arrow), yet no fibrous capsule impedes its growth into the vascular tissue of the renal sinus (curved arrows). (C) Intravenous RCC within larger involved veins (V) is nourished by a delicate capillary plexus. The three other involved lymphovascular structures (arrows) lacking a capillary plexus could be of haematogenous or lymphatic origin. Immunoperoxidase staining for smooth muscle actin (red) and CD31 (black). Fig. 2A and B reprinted with permission from Lippincott Williams & Wilkins [42]. Fig. 2C reprinted with permission from the Nature Publishing Group [45]. European Urology  , DOI: ( /j.eururo ) Copyright © 2009 European Association of Urology Terms and Conditions


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