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Innovative Liposomes as a Transfollicular Drug Delivery System: Penetration into Porcine Hair Follicles  Sascha Jung, Nina Otberg, Gisela Thiede, Heike.

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Presentation on theme: "Innovative Liposomes as a Transfollicular Drug Delivery System: Penetration into Porcine Hair Follicles  Sascha Jung, Nina Otberg, Gisela Thiede, Heike."— Presentation transcript:

1 Innovative Liposomes as a Transfollicular Drug Delivery System: Penetration into Porcine Hair Follicles  Sascha Jung, Nina Otberg, Gisela Thiede, Heike Richter, Wolfram Sterry, Steffen Panzner, Jürgen Lademann  Journal of Investigative Dermatology  Volume 126, Issue 8, Pages (August 2006) DOI: /sj.jid Copyright © 2006 The Society for Investigative Dermatology, Inc Terms and Conditions

2 Figure 1 Histological cross-section with hair follicle of a skin sample taken 3 days after application of liposome type 2. SC=stratum corneum; Bar=500μm; close up: Bar=100μm. Journal of Investigative Dermatology  , DOI: ( /sj.jid ) Copyright © 2006 The Society for Investigative Dermatology, Inc Terms and Conditions

3 Figure 2 Fluorescence image of a histological cross-section of a hair follicle, taken 7 days after application of liposome type 4. Bar=100μm. Journal of Investigative Dermatology  , DOI: ( /sj.jid ) Copyright © 2006 The Society for Investigative Dermatology, Inc Terms and Conditions

4 Figure 3 Arrangement of the test areas and their subdivisions. Pig ear with a scheme of two test areas (each 4 × 4cm) and their subdivisions (each 1 × 4cm). Biopsies were taken from a different subdivision at different time points (1hour, 3, 5, and 7 days after application). Journal of Investigative Dermatology  , DOI: ( /sj.jid ) Copyright © 2006 The Society for Investigative Dermatology, Inc Terms and Conditions


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