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Advances in Peanut Allergen Immunotherapy

Published byLaurence Joseph Modified over 6 years ago

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Presentation on theme: "Advances in Peanut Allergen Immunotherapy"— Presentation transcript:

1 Advances in Peanut Allergen Immunotherapy

2 The Skin as an Immune Organ

3 Peanut Allergy

4 Pathophysiology of Peanut Allergy

5 Skin Is an Immune Organ

6 Immunity vs Tolerance

7 LEAP: Study Design

8 LEAP: Peanut Allergy at 60 Months of Age

9 Risk Reduction for Peanut Protein Exposure

10 Sensitivity to Peanut Allergens

11 Peanut Protein in a Peanut

12 Peanut Exposure in the Community

13 Exposure Dose Calculation

14 Increasing Peanut Allergy Threshold

15 Approach of Quantitative Risk Assessment Modeling

16 Clinical Relevance of Higher Threshold

17 Peanut Allergen Immunotherapy

18 Allergen Immunotherapy Basics

19 Desensitization vs Tolerance vs SU

20 Immunotherapies in Development

21 OIT and SLIT Trial Design

22 E-OIT in Peanut-Allergic Preschool Children

23 OIT Limitations and Advantages

24 SLIT Randomized Placebo-Controlled Multicenter Trial

25 SLIT Limitations and Advantages

26 SLIT Randomized Placebo-Controlled Multicenter Trial: 3-Year Follow-Up

27 EPIT Limitations and Advantages

28 EPIT Randomized Placebo-Controlled Multicenter Trial

29 EPIT VIPES Phase 2b Randomized Controlled Trial: 2-Year Extension

30 Summary

31 Abbreviations

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