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Complicated Clostridium difficile colitis in children with cystic fibrosis: Association with gastric acid suppression?  G. Com, N. Cetin, C.E. O'Brien 

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Presentation on theme: "Complicated Clostridium difficile colitis in children with cystic fibrosis: Association with gastric acid suppression?  G. Com, N. Cetin, C.E. O'Brien "— Presentation transcript:

1 Complicated Clostridium difficile colitis in children with cystic fibrosis: Association with gastric acid suppression?  G. Com, N. Cetin, C.E. O'Brien  Journal of Cystic Fibrosis  Volume 13, Issue 1, Pages (January 2014) DOI: /j.jcf Copyright © 2013 European Cystic Fibrosis Society. Terms and Conditions

2 Fig. 1 Case #3, prior to total colectomy. Diffuse colonic wall edema and dilation of colon associated with toxic megacolon. Journal of Cystic Fibrosis  , 37-42DOI: ( /j.jcf ) Copyright © 2013 European Cystic Fibrosis Society. Terms and Conditions

3 Fig. 2 The post-operative pathology sample shows a thick pseudomembrane formed by neutrophils, epithelial debris, red blood cells, fibrin, and mucus adheres to the colonic mucosa (A) and exudate erupting from areas of mucosal erosion resembling lava erupting from a volcano (B). Journal of Cystic Fibrosis  , 37-42DOI: ( /j.jcf ) Copyright © 2013 European Cystic Fibrosis Society. Terms and Conditions


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