1. Regeneration: Organizing the Blastema in Planarians
Christian P. Petersen 
Current Biology 
Volume 27, Issue 5, Pages R181-R183 (March 2017)
DOI: /j.cub
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2. Figure 1 A coordinate system for head regeneration.
A group of cells (blue) at the far anterior of planarians expresses notum, zic-1, foxD and follistatin. Uninjured animals constitutively express slit at their midline (yellow), bmp4 on their dorsal surface (green) and wnt5 at the lateral dorsoventral boundary (green/red interface). (Top) When transplanted, this group of anterior cells can form a well-patterned ectopic axis. (Bottom) Amputation (dotted lines) causes zic-1- and foxD-dependent specification of pole progenitors (blue) from neoblast stem cells along the pre-existing midline that then migrate to the dorsoventral midpoint (green/red interface) and pattern the regenerating head blastema.
Current Biology  , R181-R183DOI: ( /j.cub )
Copyright © 2017 Elsevier Ltd Terms and Conditions