1. by Robert McMillan, Jennifer Lopez-Dee, and Joseph C. Loftus
Autoantibodies to αIIbβ3 in patients with chronic immune thrombocytopenic purpura bind primarily to epitopes on αIIb
by Robert McMillan, Jennifer Lopez-Dee, and Joseph C. Loftus
Blood
Volume 97(7):
April 1, 2001
©2001 by American Society of Hematology

2. Binding of antibodies to CHO cells expressing αIIbβ3 or αvβ3
Binding of antibodies to CHO cells expressing αIIbβ3 or αvβ3.CHO cells, expressing either αIIbβ3 (left column) or αvβ3 (right column), were incubated with platelet-associated autoantibody from ITP patients (ITP-4, -5, -6) or allo-antibody from a patient wit...
Binding of antibodies to CHO cells expressing αIIbβ3 or αvβ3.CHO cells, expressing either αIIbβ3 (left column) or αvβ3 (right column), were incubated with platelet-associated autoantibody from ITP patients (ITP-4, -5, -6) or allo-antibody from a patient with posttransfusion purpura (PTP-1), and bound antibody was detected by FACS analysis using FITC-antihuman IgG. In each panel, binding to CHO cells, expressing the glycoprotein complex (shaded profile), is compared to binding to native CHO cells (open profile).
Robert McMillan et al. Blood 2001;97:
©2001 by American Society of Hematology