1. Instructor: Prof. Chen YuZong TA: Wei Xiaona (weixiaona@nus.edu.sg)
Assignment 1 for CZ5226
Instructor: Prof. Chen YuZong
TA: Wei Xiaona

2. Cancer related pathway
Topics:
Breast Cancer
Lung Cancer
Liver Cancer
leukemia
Requirement:
Draw pathway using KEGG as template ( Assignment 1)
Find key gene in cancer (Combined analysis the information of gene’s mutation, expression level, and copy number variation ) (Assignment2)

3. draw pathway map using KEGG as template
KEGG website:

4. Tool used for draw pathway
CellDesigner Official Web Site

5. Suggestion
Cancer are very complex process and are related to many pathways. You can draw the pathways based on the role of in a cancer, such as cancer metastasis, angiogenesis and cell proliferation.
How many genes/proteins are appropriate in a pathway map?
The more detailed the better.

6. Report Requirement Clarity in present your work.
Completeness of the components in pathway.
Understanding how cancer occurred and the role of pathway in cancer .

7. Important Deadline
Divide three or four groups Deadline: 16th Feb Assignment report submission: Deadline: 31th March Contact: