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A Sweet New Role for EGFR in Cancer

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Presentation on theme: "A Sweet New Role for EGFR in Cancer"— Presentation transcript:

1 A Sweet New Role for EGFR in Cancer
Jeffrey A. Engelman, Lewis C. Cantley  Cancer Cell  Volume 13, Issue 5, Pages (May 2008) DOI: /j.ccr Copyright © 2008 Elsevier Inc. Terms and Conditions

2 Figure 1 EGFR Facilitates Glucose Transport
This cartoon depicts two functions of EGFR. (Left) EGFR homodimerizes or heterodimerizes with other ERBB family members to promote downstream growth and survival signals. (Right) EGFR binds to SGLT1 and stabilizes its expression to promote glucose uptake. Cancer Cell  , DOI: ( /j.ccr ) Copyright © 2008 Elsevier Inc. Terms and Conditions

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