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Transmission of Action Potential Across a Synapse

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Presentation on theme: "Transmission of Action Potential Across a Synapse"— Presentation transcript:

1 Transmission of Action Potential Across a Synapse

2 axon terminal synaptic cleft
Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. axon terminal synaptic vesicles enclose neuro- transmitters synaptic cleft

3 presynaptic membrane neurotransmitter postsynaptic membrane
Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. presynaptic membrane neurotransmitter postsynaptic membrane

4 Fig. 17.5d neuro- transmitter receptor Na+ postsynaptic neuron
Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. neuro- transmitter receptor Na+ postsynaptic neuron

5 axon terminal synaptic cleft
Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. axon terminal 1. After an action potential arrives at an axon terminal, Ca2+ enters, and synaptic vesicles fuse with the presynaptic membrane. Ca2+ synaptic vesicles enclose neuro- transmitters synaptic cleft

6 2. Neuro- transmitters are released and bind to receptors on the
Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. 2. Neuro- transmitters are released and bind to receptors on the postsynaptic membrane. axon terminal 1. After an action potential arrives at an axon terminal, Ca2+ enters, and synaptic vesicles fuse with the presynaptic membrane. presynaptic membrane neurotransmitter postsynaptic membrane Ca2+ synaptic vesicles enclose neuro- transmitters synaptic cleft

7 2. Neuro- transmitters are released and bind to receptors on the
Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. 2. Neuro- transmitters are released and bind to receptors on the postsynaptic membrane. axon terminal 1. After an action potential arrives at an axon terminal, Ca2+ enters, and synaptic vesicles fuse with the presynaptic membrane. presynaptic membrane neurotransmitter postsynaptic membrane Ca2+ 3. When an excitatory neuro- transmitter binds to a receptor, Na+ diffuses into the postsynaptic neuron, and an action potential begins. synaptic vesicles enclose neuro- transmitters neuro- transmitter receptor Na+ postsynaptic neuron synaptic cleft

8 2. Neuro- transmitters are released and bind to receptors on the
Copyright © The McGraw-Hill Companies, Inc. Permission required for reproduction or display. 2. Neuro- transmitters are released and bind to receptors on the postsynaptic membrane. axon terminal 1. After an action potential arrives at an axon terminal, Ca2+ enters, and synaptic vesicles fuse with the presynaptic membrane. cell body of postsynaptic neuron presynaptic membrane neurotransmitter postsynaptic membrane Ca2+ 3. When an excitatory neuro- transmitter binds to a receptor, Na+ diffuses into the postsynaptic neuron, and an action potential begins. synaptic vesicles enclose neuro- transmitters neuro- transmitter receptor Na+ postsynaptic neuron synaptic cleft

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