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Biomarkers in Nephrology: Core Curriculum 2013

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Presentation on theme: "Biomarkers in Nephrology: Core Curriculum 2013"— Presentation transcript:

1 Biomarkers in Nephrology: Core Curriculum 2013
Gearoid M. McMahon, MB, BCh, Sushrut S. Waikar, MD, MPH  American Journal of Kidney Diseases  Volume 62, Issue 1, Pages (July 2013) DOI: /j.ajkd Copyright © 2013 National Kidney Foundation, Inc. Terms and Conditions

2 Figure 1 Anatomical localization of biomarkers along the nephron. Abbreviations: ADMA, asymmetric dimethyl arginine; CTGF, connective tissue growth factor; GGT, γ-glutamyl transpeptidase; GST, glutathione-S-transferase; IL-18, interleukin 18; KIM-1, kidney injury molecule 1; LDH, lactate dehydrogenase; L-FABP, liver-type fatty acid binding protein; NAG, N-acetyl glucosaminidase; NGAL, neutrophil gelatinase-associated lipocalin. American Journal of Kidney Diseases  , DOI: ( /j.ajkd ) Copyright © 2013 National Kidney Foundation, Inc. Terms and Conditions

3 Figure 2 Pattern of change in biomarkers over time in patients with acute kidney injury following cardiac surgery. Abbreviation: NGAL, neutrophil gelatinase-associated lipocalin. Conversion factor for units: serum creatinine in mg/dL to μmol/L, ×88.4. Data from Parikh CR, et al. Postoperative biomarkers predict acute kidney injury and poor outcomes after pediatric cardiac surgery. J Am Soc Nephrol. 2011;22: American Journal of Kidney Diseases  , DOI: ( /j.ajkd ) Copyright © 2013 National Kidney Foundation, Inc. Terms and Conditions


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