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Total ion current-EMS chromatograms of SB939 and its metabolites after incubation in liver microsomal fractions for 60 min at a concentration of 50 μM.

Published byΚλυταιμνήστρα Μένθη Λιάπης Modified over 6 years ago

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Presentation on theme: "Total ion current-EMS chromatograms of SB939 and its metabolites after incubation in liver microsomal fractions for 60 min at a concentration of 50 μM."— Presentation transcript:

1 Total ion current-EMS chromatograms of SB939 and its metabolites after incubation in liver microsomal fractions for 60 min at a concentration of 50 μM. Total ion current-EMS chromatograms of SB939 and its metabolites after incubation in liver microsomal fractions for 60 min at a concentration of 50 μM. A, human liver microsomes. B, mouse liver microsomes. C, dog liver microsomes. D, rat liver microsomes. The major metabolite peaks are identified. Ramesh Jayaraman et al. Drug Metab Dispos 2011;39: Copyright © 2011 by The American Society for Pharmacology and Experimental Therapeutics

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