1. Exploring Personalized Prophylaxis in Hemophilia A

3. Introduction

4. Personalizing Therapy

5. Concept of PK Personalization

6. PK Variability

7. Individual Variability

8. Population PK Studies

9. ISTH Recommendation on Population PK Studies

10. WAPPS-Hemo Database

11. Case 1

12. Performing the PopPK Study

13. Case 1: Results From WAPPS-Hemo

14. Dose Simulations

15. Case 1: Outcomes

16. Patient-Provider Communication

17. Case 2

18. Case 2: Results From WAPPS-Hemo

19. Dosing Options

20. Case 2: Outcomes

21. Treatment Logs

22. PK Samples

23. Examples of Patients Who Should Undergo PK Studies

24. Concluding Remarks

25. Abbreviations