Download presentation
Presentation is loading. Please wait.
Published byHartono Gunawan Modified over 6 years ago
1
Beyond Making Ends Meet: DNA-PK, Metabolism, and Aging
Xiao Tian, Andrei Seluanov, Vera Gorbunova Cell Metabolism Volume 25, Issue 5, Pages (May 2017) DOI: /j.cmet Copyright © Terms and Conditions
2
Figure 1 Potential Strategies to Delay Aging Caused by Accumulation of DNA Damage DNA damage leads to aging and functional decline by generating mutations, inducing cellular senescence, and causing metabolic dysregulation due to persistent DNA damage signaling. These deleterious effects of DNA damage can be targeted either individually through elimination of senescent cells or inhibition of DNA-PK, or, more comprehensively, by developing strategies to improve DNA repair. Cell Metabolism , DOI: ( /j.cmet ) Copyright © Terms and Conditions
Similar presentations
© 2024 SlidePlayer.com. Inc.
All rights reserved.