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Activated NRAS Mediates Self-Renewal Capacity in AML by Facilitating the Mll/AF9-Specified Gene Expression Signature by Zohar Sachs, Hanh Nguyen, Nurul.

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Presentation on theme: "Activated NRAS Mediates Self-Renewal Capacity in AML by Facilitating the Mll/AF9-Specified Gene Expression Signature by Zohar Sachs, Hanh Nguyen, Nurul."— Presentation transcript:

1 Activated NRAS Mediates Self-Renewal Capacity in AML by Facilitating the Mll/AF9-Specified Gene Expression Signature by Zohar Sachs, Hanh Nguyen, Nurul Azyan Mohd Hassan, Susan K Rathe, Karen Sachs, Ernesto Diaz-Flores, Sean C Bendall, Miechaleen D Diers, Garry P. Nolan, Kevin M. Shannon, and David A. Largaespada Blood Volume 120(21): November 16, 2012 ©2012 by American Society of Hematology

2 NRAS-dependent gene expression signature recapitulates Mll/AF9 gene expression signature.
Zohar Sachs et al. Blood 2012;120:5116 ©2012 by American Society of Hematology

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