Presentation is loading. Please wait.

Presentation is loading. Please wait.

Analysis of Sustained Viral Response and Boceprevir Resistance Following Combination Treatment With Boceprevir Plus Peginterferon Alfa-2a/Ribavirin in.

Similar presentations


Presentation on theme: "Analysis of Sustained Viral Response and Boceprevir Resistance Following Combination Treatment With Boceprevir Plus Peginterferon Alfa-2a/Ribavirin in."— Presentation transcript:

1 Analysis of Sustained Viral Response and Boceprevir Resistance Following Combination Treatment With Boceprevir Plus Peginterferon Alfa-2a/Ribavirin in HCV Genotype 1 Prior Relapsers And Nonresponders

2 Study Design

3 SVR and Relapse Rates Are Consistent With RESPOND 2

4

5 Objective

6 Methodology for Resistance Analysis

7 Amino Acid Residues Associated With Resistance Can Directly or Indirectly Influence Boceprevir Binding

8 Non-SVR Patients With Postbaseline RAVs Detected: Distribution by Treatment Response Category

9 Non-SVR Patients With Post-baseline RAVs Detected: Distribution by Resistance Locus

10 Virological Response Curves for Non-SVR Patients With Postbaseline RAVs

11 SVR Based on TW4 Lead-in Response (Overall Study – BOC Arm)

12 RAVs Detected in Non-SVR Interferon Responders and Nonresponders

13 Summary

14 Acknowledgements


Download ppt "Analysis of Sustained Viral Response and Boceprevir Resistance Following Combination Treatment With Boceprevir Plus Peginterferon Alfa-2a/Ribavirin in."

Similar presentations


Ads by Google