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Published byFlorentin Croteau Modified over 6 years ago
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When Should We Suspect Hereditary Colorectal Cancer Syndrome?
Xavier Llor Clinical Gastroenterology and Hepatology Volume 10, Issue 4, Pages (April 2012) DOI: /j.cgh Copyright © 2012 AGA Institute Terms and Conditions
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Figure 1 Proposed schema for LS diagnosis. The proposed strategy incorporates the performance of MLH1 methylation and/or BRAF (V600E) point mutation analysis if that is available. IHC would start with the most common proteins responsible for LS, MSH2 and MLH1. If those were normally expressed, we would proceed to testing MSH6 and PMS2. Clinical Gastroenterology and Hepatology , DOI: ( /j.cgh ) Copyright © 2012 AGA Institute Terms and Conditions
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