3. Program Goals

4. Disclaimer

5. Overview

6. Assessing Disease Activity

7. Assessing Disease Activity (cont)

8. Surveillance Monitoring

9. Modified Rio Score

10. How Much Time Should Be Allowed to Determine Whether a DMT Is Effective?

11. Does Switching Work?

12. Stopping Natalizumab Treatment

13. Tolerability Issues

14. JCV Serology

15. Is a Washout Period Needed?

16. Is a Washout Period Needed? (cont)

17. Rebound

18. Selecting the Next Treatment Option: General Principles

19. Guidelines About Switching Are Lacking

20. Summary and Key Points

21. Abbreviations

22. References

23. References (cont)

24. References (cont)

25. References (cont)

26. References (cont)