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Published byFarida Atmadjaja Modified over 6 years ago
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Defensins Versus Bacteria: Not Just Antibiotics Anymore
Nita H. Salzman Gastroenterology Volume 134, Issue 7, Pages (June 2008) DOI: /j.gastro Copyright © 2008 AGA Institute Terms and Conditions
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Figure A model for Toxin B–defensin interaction in the intestine. In the small intestine, high concentrations of HD5 result in Toxin B aggregation and prevention of intoxication. In the large intestine, inadequate amounts of α-defensin are present to aggregate or inhibit Toxin B, resulting in epithelial intoxication, inflammation, and neutrophil infiltration. Gastroenterology , DOI: ( /j.gastro ) Copyright © 2008 AGA Institute Terms and Conditions
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