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Actin and Microtubules: Working Together to Control Spindle Polarity

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Presentation on theme: "Actin and Microtubules: Working Together to Control Spindle Polarity"— Presentation transcript:

1 Actin and Microtubules: Working Together to Control Spindle Polarity
Fengfeng L. Xu, William S. Saunders  Cancer Cell  Volume 14, Issue 3, Pages (September 2008) DOI: /j.ccr Copyright © 2008 Elsevier Inc. Terms and Conditions

2 Figure 1 Three Models of Mechanisms that May Contribute to Centrosome Clustering (A) Microtubule (MT) motors such as dynein or HSET may crosslink microtubules from adjacent centrosomes. (B) Focal adhesions (FAs) and cortical contraction may influence centrosome position through microtubule attachments. ECM = extracellular matrix. (C) FA proteins transported to centrosomes by molecular motors may affect clustering. Cancer Cell  , DOI: ( /j.ccr ) Copyright © 2008 Elsevier Inc. Terms and Conditions

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