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Deviations between serum neutralization against PV1 strains compared with PV1-RC2010.
Deviations between serum neutralization against PV1 strains compared with PV1-RC2010. (A) Relative reciprocal neutralization titers on Vero cells against PV1-RC2010 (“α-RC2010”) divided by those against Sabin-1 (“α-Sabin”). (B) Titers on Vero cells against PV1-RC2010 and against Mahoney. (C) Confirmation of partial results from A on RD cells. (D) Confirmation of results from A and C on HEp-2C cells. (E) Titers against PV1-RC2010 compared with those against WPV1 Bar65 and Tajik; (F) against PV1-RC2010 and against two VDPV type 1 strains; and (G) against the two WPV1 and VDPV strains, respectively. All on RD cells for 31 sera from the student cohort shown in A–D. Filled circles represent null deviations. Jan Felix Drexler et al. PNAS 2014;111:35: ©2014 by National Academy of Sciences
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