1. Rapid Screening of ASXL1, IDH1, IDH2, and c-CBL Mutations in de Novo Acute Myeloid Leukemia by High-Resolution Melting 
Mariam Ibáñez, Esperanza Such, José Cervera, Irene Luna, Inés Gómez-Seguí, María López-Pavía, Sandra Dolz, Eva Barragán, Oscar Fuster, Marta Llop, Rebeca Rodríguez-Veiga, Amparo Avaria, Silvestre Oltra, M. Leonor Senent, Federico Moscardó, Pau Montesinos, David Martínez-Cuadrón, Guillermo Martín, Miguel A. Sanz 
The Journal of Molecular Diagnostics 
Volume 14, Issue 6, Pages (November 2012)
DOI: /j.jmoldx
Copyright © 2012 American Society for Investigative Pathology and the Association for Molecular Pathology Terms and Conditions

2. Figure 1
HRM curves and corresponding sequences for some ASXL1 (A and B), IDH1 (C), and IDH2 (D) variations. Asterisks indicate the mutated nucleotide.
The Journal of Molecular Diagnostics  , DOI: ( /j.jmoldx )
Copyright © 2012 American Society for Investigative Pathology and the Association for Molecular Pathology Terms and Conditions

3. Figure 2
Relationship between study mutations and other common mutations in de novo acute myeloid leukemia (AML). A Circos diagram depicts the relative frequency and pairwise co-occurrence of mutations in 175 patients with newly diagnosed AML. The length of the arc corresponds to the frequency of mutations in the first gene, and the width of the ribbon corresponds to the percentage of patients who also had a mutation in the second gene. Pairwise co-occurrence of mutations is denoted only once, beginning with the first gene in the clockwise direction. ITD denotes internal tandem duplication.
The Journal of Molecular Diagnostics  , DOI: ( /j.jmoldx )
Copyright © 2012 American Society for Investigative Pathology and the Association for Molecular Pathology Terms and Conditions