1. Risk Stratification in CAD and PAD

3. COMPASS Trial Design

4. COMPASS Efficacy Outcomes

5. COMPASS PAD MALE and Major Amputation

6. COMPASS Bleeding Outcomes

7. COMPASS HF Net Clinical Benefit

8. COMPASS HF Major Bleeding

9. COMMANDER HF Design

10. Case #1: 64-Year-Old Woman

11. Case #1: 64-Year-Old Woman (cont) December 2017 Follow-Up

12. COMPASS Entry Criteria

13. Case #1: 64-Year-Old Woman (cont) July 2018 Follow-Up

14. Case #1: Meets Compass Entry Criteria

15. Rivaroxaban New European Indication

16. Case #2: 78-Year-Old Man

17. Case #2: 78-Year-Old Man CVD Prevention Strategies

18. ASCEND Aspirin for Primary Prevention in DM

19. Case #2: 78-Year-Old Man (cont) May 2018 Follow-Up

20. Case #2: 78-Year-Old Man (cont) Coronary Angiography

21. Case #2: Meets Compass Entry Criteria

22. COMMANDER HF: Patients With Recent Worsening of CHF, Reduced EF, and CAD and With No AF

23. Summary

24. Abbreviations

25. Abbreviations (cont)