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MEDICAL ILLNESS COMPLICATING PREGNANCY
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HEART DISEASE IN PREGNANCY
The cardiac failure occurs during pregnancy around 30 weeks, during labour and soon following delivery FACTORS RESPONSIBLE FOR HEART FAILURE Advanced age Cardiac arrhythmias or left ventricular hypertrophy History of previous heart failure HEART DISEASE IN PREGNANCY
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Predominant congenital lesions include
Patent ductus arteriosus atrial or ventricular septal defect pulmonary stenosis coarctation of aorta fallot’s tetralogy
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RISK FACTORS Infection Anaemia Hypertension Excessive weight gain
Multiple pregnancy Inadequate supervision
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PROGNOSIS Maternal Functional capacity of the heart
Quality of medical supervision provided Fetal Abortion IUGR Prematurity
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CLASSIFICATION Grade I – uncompromised Grade II – slightly compromised
Grade III – markedly compromised Grade IV – severely compromised
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GENERAL MANAGEMENT PRINCIPLES Early diagnosis and evaluation
Detect the high risk factors Combined care and mandatory hospital delivery
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ANTENATAL CARE Supervised in a tertiary care hospital Initial assessment in consultation with a cardiologist Counselling Special care in each visit to detect risk factors like infections
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ADVICES GIVEN Adequate rest To avoid undue excitement and strain
To avoid caffeine,alcohol,betamimetics,drugs and high calorie or spicy diet Anemia is to be corrected Cold and infection are to be avoided Adequate dental care
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ROLE OF ANTICOAGULANTS
congenital heart disease pulmonary hypertension artificial valve replacement atrial fibrillation.
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Warfarin should discontinue as soon as pregnancy is diagnosed and replaced by heparin 5000 units twice daily SC up to 12 wk. Then replace by warfarin 3mg up to 36 wks. Thereafter replaced by heparin upto 7 days of postpartum.
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ADMISSION Elective Grade I at least 2 wks prior to EDD Grade II - at 28th week specially in case of unfavourable social surrounding Grade III & IV – as soon as pregnancy is diagnosed Emergency Appearance of dyspnoea,cough,anaemia, pre-eclampsia
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MANAGEMENT DURING LABOUR
LABOUR-FIRST STAGE Position –patient should be in bed with lateral recumbant position Oxygen is to be administered if required Analgesia is best given by epidural anaesthesia Fluids should not be infused more than 75 ml/ hr to prevent pulmonary edema Careful watch of pulse and respiration Intravenous digoxin 0.5mg Cardiac monitoring and pulse oxymetry
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PROPHYLACTIC ANTIBIOTICS Antibiotic prophylaxis during labour and 48 hrs after delivery is considered appropriate
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SECOND STAGE Delay in the second stage of labour is managed by forceps or ventouse IV ergometrine with the delivery of anterior shoulder should be withheld to prevent sudden overloading of the heart
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THIRD STAGE If excess blood loss ,oxytocin can be given. IV Frusemide CESAREAN SECTION caesarean section for obstetric indications PUERPERIUM Observe closely 1st 24 hrs Oxygen is administered Hourly pulse, B.P and respiration Breast feeding is not contraindicated
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TUBERCULOSIS IN PREGNANCY
OBSTETRICAL MANAGEMENT TB is not an indication for termination of pregnancy Breast feeding is not contraindicated when a women is taking anti-tuberculous drugs Breast feeding is avoided it the infant is also taking the drugs to avoid drug overload In active lesion the baby is isolated from the mother following delivery
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BCG should be given to the baby as early as possible
Contraception –spacing can be achieved by any methods -oral contraceptives should be avoided when rifampicin is used -puerperal sterilisation should be seriously considered, if family is completed
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EPILEPSY Effects on pregnancy Fetal malformations cleft lip/plate
Mental retardation Cardiac abnormalities Limb defects IUGR Oligohydramnios Still births
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MANAGEMENT OF EPILEPSY
Phenobarbitone 60 – 180 mg daily Phenytoin 150 – 300 mg Carbamazeipine mg IV Diazepam 10 – 20 mg Folic acid 1mg throughout pregnancy Vitamin K 10 mg a day orally is to be given in the last two weeks
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THYROID DYSFUNCTION HYPERTHYRODISM Maternal risk Cardiac failure Fetal
Abortion IUGR Stillbirth Neonatal mortality
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DRUGS DRUG DOSE MAINTENANCE DOSE Carbimazole 20-60mg 5-15mg
Propylthiouracil mg mg
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Drugs can cause fetal goitre and hypothyrodism
Drugs are not contraindicated during breast feeding close monitoring of the neonatal thyroid functions is carried out. Thyroidectomy can done safely in the 2nd trimester Preconceptional counselling Oral pills is to be withheld
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HYPOTHYROIDISM Mostly related to thyroid autoimmunity Untreated hypothyroidism in early pregnancy can cause high fetal wastage in the form of abortion Stillbirth Prematurity subnormal mental development of the neonate Pre-eclampsia and anaemia are high
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Dose of pre-pregnancy state is need to increased during pregnancy
Detailed fetal anatomy scan at 18wks Termination of pregnancy with the consultation of neurologist No contraindication for breastfeeding
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