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 MISMATCH REPAIR: corrects mistakes when DNA is copied

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Presentation on theme: " MISMATCH REPAIR: corrects mistakes when DNA is copied"— Presentation transcript:

1 Enzymes proofread DNA during its replication and repair damage to existing DNA

2  MISMATCH REPAIR: corrects mistakes when DNA is copied
*one form of colon cancer is due to a defect in one of the proteins involved in this type of DNA repair

3  EXCISION REPAIR: corrects accidental changes that occur in existing DNA
-an enzyme (nuclease) cuts out damaged segment of DNA -enzymes DNA polymerase III and ligase fill in the resulting gaps *xeroderma pigmentosum is caused by an inherited defect in an excision-repair enzyme


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