1. Family Neisseriaceae
By:
Prof. Dr. Moussa

2. Commensally Neisseria are present in:
Conjunctiva
Throat
Mucous membrane
Rectum, cervix and uterus.

3. Pathogenic Neisseria are:
Neissseria meningitides.
N. gonorrhea.

4. All are +ve or All are –ve
Pathogenic
Commensal
Nutrient agar
Don’t grow
Grow
At 22°C
CO2 need
Need
Don’t need
Biochemical Reaction
Glucose
Maltose
Lactose
Sucrose
+ve
G +ve / M –ve
-ve
All are +ve or All are –ve
Pathogenecity
Gonorrhea meningitis
None

5. Pathogenic Neisseria Morphology: Gram –ve Diplococcic – kidney shape
Non-motile
Non-sporulated
Capsulated
Habitat:
N . meningitis → carried in nasal pharynx
N. gonorrhea→ no carrier, if present considered patient

6. Culture Can’t grow in N. agar or Macconkey
They are fastidious microorganism (Need blood to grow) best chocolate agar.
The selective media for isolation of pathogenic Neisseria →Thayer Martin Medium → (chocolate agar + antibiotic VCN) vancomycin Colistin Nystatin
Grow at 37°C after 24hr aerobically.
Non hemolytic
Need CO2 (5-10%)

7. What is gonorrhea? It is venereal disease (sexually transmitted)
Acute :
male → severe urethral discharge .
Female → Cervical discharge . 
Chronic :
Male →morning drops of pus and orchitis lead to sterility & systemic infection .
Female →inflammation of fallopian tubes (salpingitis)
Inflammation of ovary (oophoritis).
Cervical discharge.
Antibiotic Colistin resistance

8. (Meningococcal meningitis)
N . gonorrhea
N .meningitidis
Disease
Venereal disease
(gonorrhea)
Not venereal disease
(Meningococcal meningitis)
Infection
High morbidity and
low mortality
High mortality and
low morbidity
Acid production from:
Glucose
Maltose
Lactose
sucrose
+ve
-ve

9. THANK YOU