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The Digestive System and Body Metabolism

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1 The Digestive System and Body Metabolism
Copyright © 2015 Pearson Education, Inc. publishing as Benjamin Cummings

2 The Digestive System and Body Metabolism
Digestion Breakdown of ingested food Absorption Passage of nutrients into the blood Metabolism Production of cellular energy (ATP) Slide 14.1 Copyright © 2015 Pearson Education, Inc. publishing as Benjamin Cummings

3 Organs of the Digestive System
Two main groups Alimentary canal – continuous coiled hollow tube – 26 feet long Accessory digestive organs Slide 14.2a Copyright © 2015 Pearson Education, Inc. publishing as Benjamin Cummings

4 Organs of the Digestive System
Figure 14.1 Slide 14.2b Copyright © 2015 Pearson Education, Inc. publishing as Benjamin Cummings

5 Organs of the Alimentary Canal
Mouth Pharynx Esophagus Stomach Small intestine Large intestine Anus Slide 14.3 Copyright © 2015 Pearson Education, Inc. publishing as Benjamin Cummings

6 Mouth & Saliva Mastication means the chewing of food
Mixture of mucus and fluids helps to form a food bolus Initiation of swallowing by the tongue Contains salivary amylase to begin starch digestion Slide 14.34 Copyright © 2015 Pearson Education, Inc. publishing as Benjamin Cummings

7 Mouth (Oral Cavity) Anatomy
Lips (labia) – protect the anterior opening Cheeks – form the lateral walls Hard palate – forms the anterior roof Soft palate – forms the posterior roof Uvula – fleshy projection of the soft palate Figure 14.2a Slide 14.4 Copyright © 2015 Pearson Education, Inc. publishing as Benjamin Cummings

8 Mouth (Oral Cavity) Anatomy
Vestibule – space between lips externally and teeth and gums internally Tongue – attached at hyoid and styloid processes of the skull, and by the lingual frenulum Figure 14.2a Slide 14.5 Copyright © 2015 Pearson Education, Inc. publishing as Benjamin Cummings

9 Mouth (Oral Cavity) Anatomy
Tongue – frenulum filiform papillae fungiform papillae circumvallate papillae foliate papillae Figure 14.2a Slide 14.5 Copyright © 2015 Pearson Education, Inc. publishing as Benjamin Cummings

10

11 Copyright 2009, John Wiley & Sons, Inc.
The three major salivary glands- parotid, sublingual, and submandibular Copyright 2009, John Wiley & Sons, Inc.

12 Classification of Teeth
Deciduous teeth (milk teeth): 20 that fall out from 6-12 yrs Adult teeth: 32 (28 is typical) 4 wisdom teeth are often pulled Incisors: 8 teeth for cutting Canines Premolars Molars Slide 14.36a Copyright © 2015 Pearson Education, Inc. publishing as Benjamin Cummings

13 Classification of Teeth
Figure 14.9 Slide 14.36b Copyright © 2015 Pearson Education, Inc. publishing as Benjamin Cummings

14 Enamel is the hardest substance in the body
Teeth are alive and have blood vessels and nerves Gum disease can cause teeth to eventually fall out- So brush daily.

15 Structures of the mouth (oral cavity)
Copyright 2009, John Wiley & Sons, Inc.

16 Pharynx Function Serves as a passageway for air and food
4-5 inches long Deglutition: Slide 14.9 Copyright © 2015 Pearson Education, Inc. publishing as Benjamin Cummings

17 Pharynx Anatomy Nasopharynx – not part of the digestive system
Oropharynx – posterior to oral cavity Laryngopharynx – area before trachea and esophagus Figure 14.2a Slide 14.8 Copyright © 2015 Pearson Education, Inc. publishing as Benjamin Cummings

18 Esophagus Runs from pharynx to stomach through the diaphragm
Conducts food by peristalsis (slow rhythmic squeezing) What is reverse peristalsis? Passageway for food only (respiratory system branches off after the pharynx) Slide 14.10 Copyright © 2015 Pearson Education, Inc. publishing as Benjamin Cummings

19 Stomach Anatomy Located on the left side of the abdominal cavity
Acidic: so basically bacteria free Slide 14.15a Copyright © 2015 Pearson Education, Inc. publishing as Benjamin Cummings

20 Stomach Anatomy Regions of the stomach
Cardiac region – near the heart Fundus – top portion Body – middle section Pylorus – funnel-shaped terminal end Rugae – internal folds of the mucosa External regions Lesser curvature Greater curvature Slide 14.15b Copyright © 2015 Pearson Education, Inc. publishing as Benjamin Cummings

21 Stomach Anatomy Food enters the stomach at the cardiac sphincter
Food empties into the small intestine at the pyloric sphincter Slide 14.16a Copyright © 2015 Pearson Education, Inc. publishing as Benjamin Cummings

22 Stomach Anatomy Slide 14.17 Figure 14.4a
Copyright © 2015 Pearson Education, Inc. publishing as Benjamin Cummings

23 Stomach Functions Acts as a storage tank for food
Absorbs: (Fats just sit there) Water Sugars (from Carbs) – enzymes Proteins – enzymes Alcohols Slide 14.18 Copyright © 2015 Pearson Education, Inc. publishing as Benjamin Cummings

24 Specialized Mucosa of the Stomach
– produce a sticky alkaline mucus ulcer – produce protein-digesting enzymes (pepsinogens) – produce hydrochloric acid Slide 14.19 Copyright © 2015 Pearson Education, Inc. publishing as Benjamin Cummings

25 Structure of the Stomach Mucosa
Figure 14.4b, c Slide 14.20b Copyright © 2015 Pearson Education, Inc. publishing as Benjamin Cummings

26 Stomach Functions Peristalsis-muscular contractions
Chemical breakdown of protein begins Delivers chyme (processed food) to the small intestine Slide 14.18 Copyright © 2015 Pearson Education, Inc. publishing as Benjamin Cummings

27 18-21 feet long “Dogs Just Itch!
Subdivisions of the Small Intestine 18-21 feet long “Dogs Just Itch! Duodenum – about 1+ foot Attached to the stomach; acidic Curves around the head of the pancreas Jejunum – roughly 8-9 ft Attaches anteriorly to the duodenum Ileum – about 6-12 ft? Extends from jejunum to large intestine; neutral pH Slide 14.22 Copyright © 2015 Pearson Education, Inc. publishing as Benjamin Cummings

28 Villi of the Small Intestine
Fingerlike structures formed by the mucosa Give the small intestine more surface area Figure 14.7a Slide 14.24 Copyright © 2015 Pearson Education, Inc. publishing as Benjamin Cummings

29 Microvilli of the Small Intestine
Small projections of the plasma membrane Found on absorptive cells Muscular tube extending from the pyloric sphincter to the ileocecal valve Suspended from the posterior abdominal wall by the mesentery Figure 14.7c Slide 14.25 Copyright © 2015 Pearson Education, Inc. publishing as Benjamin Cummings

30 Structures Involved in Absorption of Nutrients
Absorptive cells Blood capillaries Lacteals (specialized lymphatic capillaries) Figure 14.7b Slide 14.26 Copyright © 2015 Pearson Education, Inc. publishing as Benjamin Cummings

31 Small Intestine The body’s major digestive organ
Site of all nutrient absorption into the blood Bile Lots of enzymes to finish break down of proteins and carbs. Begins and ends break down of fats here. Pancreatic juices Slide 14.21 Copyright © 2015 Pearson Education, Inc. publishing as Benjamin Cummings

32 Propulsion in the Small Intestine
Peristalsis is the major means of moving food Segmental movements Mix chyme with digestive juices Aid in propelling food Slide 14.60 Copyright © 2015 Pearson Education, Inc. publishing as Benjamin Cummings

33 Processes of the Digestive System
Peristalsis – alternating waves of contraction Segmentation – moving materials back and forth to aid in mixing Figure 14.12 Slide 14.42b Copyright © 2015 Pearson Education, Inc. publishing as Benjamin Cummings

34 Large Intestine Larger in diameter, but shorter than the small intestine Frames the internal abdomen Slide 14.28 Copyright © 2015 Pearson Education, Inc. publishing as Benjamin Cummings

35 Large Intestine Slide 14.28 Figure 14.8
Copyright © 2015 Pearson Education, Inc. publishing as Benjamin Cummings

36 Structures of the Large Intestine
Cecum – saclike first part of the large intestine Appendix Accumulation of lymphatic tissue that sometimes becomes inflamed (appendicitis) Hangs from the cecum Slide 14.30a Copyright © 2015 Pearson Education, Inc. publishing as Benjamin Cummings

37 Structures of the Large Intestine
Colon Ascending Transverse Descending S-shaped sigmoidal Rectum Anus – external body opening Slide 14.30b Copyright © 2015 Pearson Education, Inc. publishing as Benjamin Cummings

38 Functions of the Large Intestine
Does not participate in digestion of food Absorption of water dissolved vitamins & minerals Eliminates indigestible food from the body as feces We lack the enzyme cellulase and cannot digest veggies and cellulose We live in symbiosis with bacteria; half our fecal matter is bacteria Slide 14.29 Copyright © 2015 Pearson Education, Inc. publishing as Benjamin Cummings

39 Food Breakdown and Absorption in the Large Intestine
No digestive enzymes are produced Cholera is a bacteria that: Slide 14.61 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings

40 Propulsion in the Large Intestine
Sluggish peristalsis Mass movements Slow, powerful movements Occur three to four times per day Presence of feces in the rectum causes a defecation reflex Internal anal sphincter is relaxed Defecation occurs with relaxation of the voluntary (external) anal sphincter Slide 14.62 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings

41 Accessory Digestive Organs
(Salivary glands) (Teeth) Pancreas Liver Gall bladder Slide 14.32 Copyright © 2015 Pearson Education, Inc. publishing as Benjamin Cummings

42 Liver Largest gland in the body
Located on the right side of the body under the diaphragm Connected to the gall bladder via the common hepatic duct Slide 14.39 Copyright © 2015 Pearson Education, Inc. publishing as Benjamin Cummings

43 Role of the Liver in Metabolism
Several roles in digestion- makes bile Detoxifies drugs and alcohol Degrades hormones Produce cholesterol, blood proteins (albumin and clotting proteins) Plays a central role in metabolism Slide 14.77 Copyright © 2015 Pearson Education, Inc. publishing as Benjamin Cummings

44 Bile Produced by cells in the liver Composition Bile salts
Bile pigment (mostly bilirubin from the breakdown of hemoglobin) Cholesterol, Phospholipids, Electrolytes Slide 14.40 Copyright © 2015 Pearson Education, Inc. publishing as Benjamin Cummings

45 Gall Bladder Sac found in hollow fossa of liver
Stores bile from the liver by way of the cystic duct Bile is introduced into the duodenum in the presence of fatty food Gallstones can cause blockages Slide 14.41 Copyright © 2015 Pearson Education, Inc. publishing as Benjamin Cummings

46 Pancreas Produces a wide spectrum of digestive enzymes that break down all categories of food Enzymes are secreted into the duodenum Alkaline fluid introduced with enzymes neutralizes acidic chyme Endocrine products of pancreas Insulin Glucagons Slide 14.38 Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings

47 Messentary Identified as organ in January of 2017
Its function is still largely unknown

48 Digestive processes

49 Processes of the Digestive System
Chemical Digestion Enzymes chemically break down food molecules into their building blocks Each major food group uses different enzymes Carbohydrates are broken to simple sugars Proteins are broken to amino acids Fats are broken to fatty acids and alcohols Slide 14.44 Copyright © 2015 Pearson Education, Inc. publishing as Benjamin Cummings

50 Chemical Digestion in the Small Intestine
Source of enzymes that are mixed with chyme Intestinal cells Pancreas Bile enters from the gall bladder Slide 14.23a Copyright © 2015 Pearson Education, Inc. publishing as Benjamin Cummings

51 Control of Digestive Activity
Stimuli include: Stretch of the organ pH of the contents Presence of breakdown products Reflexes include: Activation or inhibition of glandular secretions Smooth muscle activity Slide 14.47b Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings

52 Chemical Digestion in the Small Intestine
Figure 14.6 Slide 14.23b Copyright © 2015 Pearson Education, Inc. publishing as Benjamin Cummings

53 Processes of the Digestive System
Ingestion – getting food into the mouth Propulsion – moving foods from one region of the digestive system to another Slide 14.42a Copyright © 2015 Pearson Education, Inc. publishing as Benjamin Cummings

54 Processes of the Digestive System
Mechanical digestion Mixing of food in the mouth by the tongue Churning of food in the stomach Segmentation in the small intestine Slide 14.43 Copyright © 2015 Pearson Education, Inc. publishing as Benjamin Cummings

55 Processes of the Digestive System
Figure 14.11 Slide 14.46 Copyright © 2015 Pearson Education, Inc. publishing as Benjamin Cummings

56 Nutrition Nutrient – substance used by body for growth, maintenance, and repair Categories of nutrients Water Minerals: metabolic reactions Carbohydrates: provide energy; simple sugars, starches, fiber- 4cal/gram Lipids: energy, cell membranes– 9cal/gram Proteins: muscle composition, growth & repair, amino acids; 4cal/gram Vitamins: regulate body processes Slide 14.63 Copyright © 2015 Pearson Education, Inc. publishing as Benjamin Cummings

57 Body Energy Balance Energy intake = total energy output (heat + work + energy storage) Energy intake is liberated during food oxidation Energy output Heat is usually about 60% Storage energy is in the form of fat or glycogen. A pound of fat= 3500 Calories What is healthy? How do you drop a pound? Slide 14.83 Copyright © 2015 Pearson Education, Inc. publishing as Benjamin Cummings


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