1. Volume 24, Issue 4, Pages 275-279 (December 2017)
Irinotecan chemotherapy-induced intestinal oxidative stress: Underlying causes of disturbed mucosal water and electrolyte transport 
Kaïs Rtibi, Slimen Selmi, Dhekra Grami, Hichem Sebai, Mohamed Amri, Lamjed Marzouki 
Pathophysiology 
Volume 24, Issue 4, Pages (December 2017)
DOI: /j.pathophys
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2. Pathophysiology 2017 24, 275-279DOI: (10.1016/j.pathophys.2017.07.002)
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3. Fig. 1
Histological examination of intestinal mucosa after irinotecan injection (200mgkg−1): (A) showed a normal mucosa with intact epithelial surface, (B) presented an epithelial destruction and inflammatory cells infiltrate and (C) indicated the histological scores for intestinal mucositis. #: p<0.05 compared to NaCl group. Values are means±SEM (n=10).
Pathophysiology  , DOI: ( /j.pathophys )
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4. Fig. 2
Effects of a single intraperitoneal injection of irinotecan (200mgkg−1) on protein and sulfhydryl groups levels in intestinal mucosa of rats. #: p<0.05 compared to NaCl group. Values are means±SEM (n=10).
Pathophysiology  , DOI: ( /j.pathophys )
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5. Fig. 3
Effects of a single intraperitoneal injection of irinotecan (200mgkg−1) on MDA level and MPO activity in intestinal mucosa of rats. #: p<0.05 compared to NaCl group. Values are means±SEM (n=10).
Pathophysiology  , DOI: ( /j.pathophys )
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6. Fig. 4
Effects of a single intraperitoneal injection of irinotecan (200mgkg−1) on enzymatic antioxidant activities (superoxide dismutase, catalase and glutathione peroxidase) in intestinal mucosa of rats. #: p<0.05 compared to NaCl group. Values are means±SEM (n=10).
Pathophysiology  , DOI: ( /j.pathophys )
Copyright © 2017 Elsevier B.V. Terms and Conditions