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L. A. Tafur, P. Taura, A. Blasi, J. Beltran, G. Martinez-Palli, J

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Presentation on theme: "L. A. Tafur, P. Taura, A. Blasi, J. Beltran, G. Martinez-Palli, J"— Presentation transcript:

1 Rotation thromboelastometry velocity curve predicts blood loss during liver transplantation 
L.A. Tafur, P. Taura, A. Blasi, J. Beltran, G. Martinez-Palli, J. Balust, J.C. Garcia-Valdecasas  British Journal of Anaesthesia  Volume 117, Issue 6, Pages (December 2016) DOI: /bja/aew344 Copyright © 2016 The Author(s) Terms and Conditions

2 Fig 1 Principal characteristics of thromboelastometry parameters and first derivative parameters of the waveform (V-curve) generated by clotting of whole blood clot formation. CT (s) is the clotting time, MCF (mm) is the maximum amplitude of clot formation, MaxVel (mm s−1) is the maximum velocity of clot formation, t-MaxVel (s) is the time to reach the maximum velocity of clot formation, and AUC represents the area under the velocity curve and indicates the maximum clot formation, an indirect measurement of clot strength. British Journal of Anaesthesia  , DOI: ( /bja/aew344) Copyright © 2016 The Author(s) Terms and Conditions

3 Fig 2 Receiver operating characteristic (ROC) curves of the V-curve parameters used for assessing the ability to discriminate between patients with high and low blood loss. Area under the ROC curve≤ 0.5, prediction of blood loss not better than chance; area under the ROC curve = 1.0, perfect prediction. P1(left panel). In A, ROC curves including all patients (n=198): t-MaxVel, area value of 0.69 (95% CI; ). In B, patients with viral hepatitis (n=93): t-MaxVel, area value of 0.73 ( ). In C, patients with alcohol hepatitis (n=43): t-MaxVel, area value of 0.83 ( ). P2 (right panel). In A, ROC curves including all patients: t-MaxVel, area value of 0.62 (95% CI; ). In B, patients with viral hepatitis: t-MaxVel, area value of 0.64 (95% CI; ). In C, patients with alcohol hepatitis: t-MaxVel, area value of 0.73 (95% CI; ). In all scenarios, the ROC curves of MaxVel, AUC, and mv/t-m showed values<0.5. British Journal of Anaesthesia  , DOI: ( /bja/aew344) Copyright © 2016 The Author(s) Terms and Conditions


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